Difference between revisions of "CD20"

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{{ Infobox immunostain
| Name      = {{PAGENAME}}
| Image      = Diffuse large B cell lymphoma (4) CD20.jpg
| Width      =
| Caption    = CD20 staining in a [[DLBCL]].
| Abbrev    =
| Synonyms  =
| Similar    = CD79a, PAX5
| Clones    =     
| Use        = B-cell lymphomas
| Subspecial = [[hematopathology]]
| Pattern    = membranous
| Positive  = most B-cell lymphomas
| Negative  =
| Other      =
}}
'''CD20''' is a B-cell marker. It is positive in most B-cell lymphoma.
'''CD20''' is a B-cell marker. It is positive in most B-cell lymphoma.


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*ALK+ large B-cell lymphoma.
*ALK+ large B-cell lymphoma.
*Classical [[Hodgkin's lymphoma]].
*Classical [[Hodgkin's lymphoma]].
===Abberant faint positive===
*T-cell lymphoma/leukemia - rare.<ref name=pmid27980301>{{Cite journal  | last1 = Kawano | first1 = R. | last2 = Niino | first2 = D. | last3 = Ohshima | first3 = K. | title = Six Cases of CD20-Positive Adult T-Cell Leukemia. | journal = J Clin Exp Hematop | volume = 56 | issue = 2 | pages = 119-125 | month =  | year = 2016 | doi = 10.3960/jslrt.56.119 | PMID = 27980301 }}</ref>


==See also==
==See also==

Latest revision as of 03:51, 19 April 2019

CD20
Immunostain in short

CD20 staining in a DLBCL.
Similar stains CD79a, PAX5
Use B-cell lymphomas
Subspeciality hematopathology
Normal staining pattern membranous
Positive most B-cell lymphomas

CD20 is a B-cell marker. It is positive in most B-cell lymphoma.

Lymphomas

Negative B cell lymphomas

Abberant faint positive

  • T-cell lymphoma/leukemia - rare.[2]

See also

References

  1. Teruya-Feldstein, J.; Chiao, E.; Filippa, DA.; Lin, O.; Comenzo, R.; Coleman, M.; Portlock, C.; Noy, A. (Nov 2004). "CD20-negative large-cell lymphoma with plasmablastic features: a clinically heterogenous spectrum in both HIV-positive and -negative patients.". Ann Oncol 15 (11): 1673-9. doi:10.1093/annonc/mdh399. PMID 15520070.
  2. Kawano, R.; Niino, D.; Ohshima, K. (2016). "Six Cases of CD20-Positive Adult T-Cell Leukemia.". J Clin Exp Hematop 56 (2): 119-125. doi:10.3960/jslrt.56.119. PMID 27980301.