Difference between revisions of "CD10"

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[[File:Kidney cd10 ihc.jpg|thumb|right|250px|CD10 staining in normal [[kidney]].]]
'''CD10''' is a commonly used [[immunostain]].
'''CD10''' is a commonly used [[immunostain]].


==Positive==
==Positive==
*[[Clear cell renal cell carcinoma]].
===Benign===
*Benign liver.<ref name=pmid14755758/>
*Benign liver.<ref name=pmid14755758/>
*[[Hepatocellular carcinoma]].<ref name=pmid14755758>{{Cite journal  | last1 = Lin | first1 = F. | last2 = Abdallah | first2 = H. | last3 = Meschter | first3 = S. | title = Diagnostic utility of CD10 in differentiating hepatocellular carcinoma from metastatic carcinoma in fine-needle aspiration biopsy (FNAB) of the liver. | journal = Diagn Cytopathol | volume = 30 | issue = 2 | pages = 92-7 | month = Feb | year = 2004 | doi = 10.1002/dc.10419 | PMID = 14755758 }}</ref>
*[[Endometriosis]] - stains the stroma.<ref name=Ref_DCHH236>{{Ref DCHH|236}}</ref>


===Lymphoma===
===Lymphoma===
*[[Follicular lymphoma]].
*[[Follicular lymphoma]].
*[[Diffuse large B-cell lymphoma]].
*[[Diffuse large B-cell lymphoma]].
===Other tumours===
*[[Clear cell renal cell carcinoma]].
*[[Hepatocellular carcinoma]].<ref name=pmid14755758>{{Cite journal  | last1 = Lin | first1 = F. | last2 = Abdallah | first2 = H. | last3 = Meschter | first3 = S. | title = Diagnostic utility of CD10 in differentiating hepatocellular carcinoma from metastatic carcinoma in fine-needle aspiration biopsy (FNAB) of the liver. | journal = Diagn Cytopathol | volume = 30 | issue = 2 | pages = 92-7 | month = Feb | year = 2004 | doi = 10.1002/dc.10419 | PMID = 14755758 }}</ref>
*[[Endometrial stromal sarcoma]].
*[[Solid pseudopapillary tumour]].
==Variable==
*Tumours of [[adrenal gland]].<ref name=pmid20390424>{{Cite journal  | last1 = Mete | first1 = O. | last2 = Kapran | first2 = Y. | last3 = Güllüoğlu | first3 = MG. | last4 = Kiliçaslan | first4 = I. | last5 = Erbil | first5 = Y. | last6 = Senyürek | first6 = YG. | last7 = Dizdaroğlu | first7 = F. | title = Anti-CD10 (56C6) is expressed variably in adrenocortical tumors and cannot be used to discriminate clear cell renal cell carcinomas. | journal = Virchows Arch | volume = 456 | issue = 5 | pages = 515-21 | month = May | year = 2010 | doi = 10.1007/s00428-010-0901-0 | PMID = 20390424 }}</ref>
==Negative==
*[[Clear cell papillary renal cell carcinoma]].


==See also==
==See also==

Revision as of 15:52, 9 August 2016

CD10 staining in normal kidney.

CD10 is a commonly used immunostain.

Positive

Benign

Lymphoma

Other tumours

Variable

Negative

See also

References

  1. 1.0 1.1 Lin, F.; Abdallah, H.; Meschter, S. (Feb 2004). "Diagnostic utility of CD10 in differentiating hepatocellular carcinoma from metastatic carcinoma in fine-needle aspiration biopsy (FNAB) of the liver.". Diagn Cytopathol 30 (2): 92-7. doi:10.1002/dc.10419. PMID 14755758.
  2. Tadrous, Paul.J. Diagnostic Criteria Handbook in Histopathology: A Surgical Pathology Vade Mecum (1st ed.). Wiley. pp. 236. ISBN 978-0470519035.
  3. Mete, O.; Kapran, Y.; Güllüoğlu, MG.; Kiliçaslan, I.; Erbil, Y.; Senyürek, YG.; Dizdaroğlu, F. (May 2010). "Anti-CD10 (56C6) is expressed variably in adrenocortical tumors and cannot be used to discriminate clear cell renal cell carcinomas.". Virchows Arch 456 (5): 515-21. doi:10.1007/s00428-010-0901-0. PMID 20390424.