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Difference between revisions of "Burkitt lymphoma"
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'''Burkitt lymphoma''', abbreviated '''BL''', is an uncommon | '''Burkitt lymphoma''', abbreviated '''BL''', is an uncommon [[lymphoma]] with medium-sized cells. | ||
==General== | ==General== | ||
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==Pathophysiology== | ==Pathophysiology== | ||
*Origin cell: germinal centre B cells (favoured) vs. memory B cells.<ref name=pmid12610094/> | *Origin cell: germinal centre B cells (favoured) vs. memory B cells.<ref name=pmid12610094/> | ||
==Microscopic== | ==Microscopic== | ||
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Image: [http://en.wikipedia.org/wiki/File:Burkitt_lymphoma,_H%26E.jpg Starry-sky pattern - Ed Uthman (WC)]. | Image: [http://en.wikipedia.org/wiki/File:Burkitt_lymphoma,_H%26E.jpg Starry-sky pattern - Ed Uthman (WC)]. | ||
==IHC== | |||
Features: | |||
*CD20 +ve. | |||
*CD10 +ve. | |||
*BCL6 +ve. | |||
*EBER +ve. | |||
Others: | |||
*BCL2 -ve. | |||
==Cytologic definition== | |||
*t(8;14) (q24;q32) translocation + a few variants or c-myc rearrangement.<ref name=pmid12610094/> | |||
==See also== | ==See also== | ||