Difference between revisions of "Brenner tumour"

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#redirect [[Ovarian tumours#Brenner tumour]]
The '''Brenner tumour''' is an [[ovarian tumour]] in the epithelial group of ovarian tumours.


==General==
*Fits into the ''transistional cell tumours'' category - in the surface epithelial group of ovarian tumours.
===Epidemiology===
*Mostly benign clinical course.
*Thought to arise from [[Walthard cell rest]].
*Frequently an incidental finding, i.e. oophorectomy was done for another reason.
*May be malignant.
==Gross==
Features:<ref name=pmid21897739>{{Cite journal  | last1 = Borah | first1 = T. | last2 = Mahanta | first2 = RK. | last3 = Bora | first3 = BD. | last4 = Saikia | first4 = S. | title = Brenner tumor of ovary: An incidental finding. | journal = J Midlife Health | volume = 2 | issue = 1 | pages = 40-1 | month = Jan | year = 2011 | doi = 10.4103/0976-7800.83273 | PMID = 21897739 |PMC = 3156501}}</ref>
*Classically solid, well-circumscribed, light yellow.
*May be cystic.
Note:
*Borderline tumours classically solid and cystic with papillary projections into the cystic component.<ref name=pmid21897739/>
==Microscopic==
Features:
*Nests of transitional epithelium with cells that have:<ref name=Ref_PBoD1098>{{Ref PBoD|1098}}</ref>
**A "[[coffee bean nucleus]]".
***Elliptical shape (nucleus).
***Nuclear grooves.<ref name=pathout_brenner>URL: [http://www.pathologyoutlines.com/ovarytumor.html#brennergen http://www.pathologyoutlines.com/ovarytumor.html#brennergen]. Accessed on: 8 February 2011.</ref>
***Distinct nucleoli.
**Moderate-to-abundant gray/pale cytoplasm.
*Dense fibrous stroma around nests.
Notes:
*Main DDx of Coffee bean nucleus = [[granulosa cell tumour]].
*Stromal component may be predominant.
DDx:
*[[Ovarian fibroma]].
*[[Thecoma]].
===Images===
<gallery>
Image:Brenner tumour high mag cropped.jpg | BT - cropped - high mag. (WC)
Image:Brenner tumour high mag.jpg | BT - high mag. (WC)
Image:Brenner tumour intermed mag.jpg | BT - intermed. mag. (WC)
</gallery>
==See also==
*[[Ovarian tumours]].
==References==
{{Reflist|2}}
[[Category:Ovarian tumours]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]
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