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Difference between revisions of "Breast pathology"
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→Weird stuff: +hamartoma
(→Lactational changes: another AKA) |
(→Weird stuff: +hamartoma) |
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=Weird stuff= | =Weird stuff= | ||
Like in all niches of pathology... there is weird stuff. | Like in all niches of pathology... there is weird stuff. | ||
==Mammary hamartoma== | |||
===General=== | |||
*Benign. | |||
*Disordered growth. | |||
See: ''[[hamartoma]]''. | |||
===Gross=== | |||
*Well-circumscribed - '''key feature'''. | |||
===Microscopic=== | |||
Features:<ref name=Ref_BP117>{{Ref BP|117}}</ref> | |||
*Disordered arrangement of ductal and lobular structures. | |||
*Normal arrangement of cells with in the ductal structures, i.e. myoepithelium and epithelium present. | |||
DDx: | |||
*[[Fibroadenoma]]. | |||
*[[Phyllodes tumour]]. | |||
Image: | |||
*[http://www.breastpathology.info/sub-pages-iotw/2008/18.html Mammary hamartoma (breastpathology.info)]. | |||
===IHC=== | |||
*None - it's a [[H&E]] diagnosis. | |||
==Collagenous spherulosis== | ==Collagenous spherulosis== | ||
*[[AKA]] ''mucinous spherulosis'', [[AKA]] ''spherulosis''.<ref name=stanford_collspher>URL: [http://surgpathcriteria.stanford.edu/breast/collspher/ http://surgpathcriteria.stanford.edu/breast/collspher/]. Accessed on: 4 September 2011.</ref> | *[[AKA]] ''mucinous spherulosis'', [[AKA]] ''spherulosis''.<ref name=stanford_collspher>URL: [http://surgpathcriteria.stanford.edu/breast/collspher/ http://surgpathcriteria.stanford.edu/breast/collspher/]. Accessed on: 4 September 2011.</ref> | ||
===General=== | ===General=== | ||
*Benign. | |||
*Almost always an incidental finding. | *Almost always an incidental finding. | ||
*Can mimic [[ADH]], [[DCIS]], [[adenoid cystic carcinoma]].<ref name=pmid16330938>{{Cite journal | last1 = Resetkova | first1 = E. | last2 = Albarracin | first2 = C. | last3 = Sneige | first3 = N. | title = Collagenous spherulosis of breast: morphologic study of 59 cases and review of the literature. | journal = Am J Surg Pathol | volume = 30 | issue = 1 | pages = 20-7 | month = Jan | year = 2006 | doi = | PMID = 16330938 }}</ref> | *Can mimic [[ADH]], [[DCIS]], [[adenoid cystic carcinoma]].<ref name=pmid16330938>{{Cite journal | last1 = Resetkova | first1 = E. | last2 = Albarracin | first2 = C. | last3 = Sneige | first3 = N. | title = Collagenous spherulosis of breast: morphologic study of 59 cases and review of the literature. | journal = Am J Surg Pathol | volume = 30 | issue = 1 | pages = 20-7 | month = Jan | year = 2006 | doi = | PMID = 16330938 }}</ref> | ||
**Epidemiologically, it may be associated with [[LCIS]].<ref name=pmid16330938/> | **Epidemiologically, it may be associated with [[LCIS]].<ref name=pmid16330938/> | ||
===Microscopic=== | ===Microscopic=== | ||