48,460
edits
Difference between revisions of "Breast pathology"
Jump to navigation
Jump to search
→Phyllodes tumour
| Line 314: | Line 314: | ||
The name comes from the word "leaf"; with imagination or psychotropic drugs, it may look like one (the epithelial component = the veins of the leaf). | The name comes from the word "leaf"; with imagination or psychotropic drugs, it may look like one (the epithelial component = the veins of the leaf). | ||
=== | ===General=== | ||
*Wide excision -- this differs from fibroadenoma (just local excision). | *Wide excision -- this differs from fibroadenoma (just local excision). | ||
*Approximately 6% are malignant.<ref name=pmid12689668>{{cite journal |author=Guerrero MA, Ballard BR, Grau AM |title=Malignant phyllodes tumor of the breast: review of the literature and case report of stromal overgrowth |journal=Surg Oncol |volume=12 |issue=1 |pages=27–37 |year=2003 |month=July |pmid=12689668 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0960740403000057}}</ref> | *Approximately 6% are malignant.<ref name=pmid12689668>{{cite journal |author=Guerrero MA, Ballard BR, Grau AM |title=Malignant phyllodes tumor of the breast: review of the literature and case report of stromal overgrowth |journal=Surg Oncol |volume=12 |issue=1 |pages=27–37 |year=2003 |month=July |pmid=12689668 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0960740403000057}}</ref> | ||
| Line 331: | Line 331: | ||
*[http://commons.wikimedia.org/wiki/File:Phyllodes_tumour.jpg Phyllodes tumour (WC)]. | *[http://commons.wikimedia.org/wiki/File:Phyllodes_tumour.jpg Phyllodes tumour (WC)]. | ||
===Malignant phyllodes?=== | ====Malignant phyllodes?==== | ||
Features of malignancy:<ref name=pmid17932112>{{cite journal |author=Taira N, Takabatake D, Aogi K, ''et al'' |title=Phyllodes tumor of the breast: stromal overgrowth and histological classification are useful prognosis-predictive factors for local recurrence in patients with a positive surgical margin |journal=Jpn. J. Clin. Oncol. |volume=37 |issue=10 |pages=730-6 |year=2007 |month=October |pmid=17932112 |doi=10.1093/jjco/hym099 |url=http://jjco.oxfordjournals.org/cgi/reprint/37/10/730}}</ref> | Features of malignancy:<ref name=pmid17932112>{{cite journal |author=Taira N, Takabatake D, Aogi K, ''et al'' |title=Phyllodes tumor of the breast: stromal overgrowth and histological classification are useful prognosis-predictive factors for local recurrence in patients with a positive surgical margin |journal=Jpn. J. Clin. Oncol. |volume=37 |issue=10 |pages=730-6 |year=2007 |month=October |pmid=17932112 |doi=10.1093/jjco/hym099 |url=http://jjco.oxfordjournals.org/cgi/reprint/37/10/730}}</ref> | ||
*Stromal cellular atypia. | *Stromal cellular atypia. | ||
*Mitotic activity in 10 [[HPF]]s. | *Mitotic activity in 10 [[HPF]]s. | ||
**"HPF" is not adequately defined - see [[HPFitis]]. The authors should be spanked. | |||
*Stromal overgrowth -- epithelial elements absent in one low power field (x40).<ref name=pmid17932112/> | *Stromal overgrowth -- epithelial elements absent in one low power field (x40).<ref name=pmid17932112/> | ||
**"LPF" is not adequately defined - see [[LPFitis]]. The authors should be spanked. | |||
A comparison between benign and malignant phyllodes - adapted from Taira et al.<ref name=pmid17932112/> | |||
{| class="wikitable" | {| class="wikitable" | ||
| || '''Benign''' || '''Malignant''' | | || '''Benign''' || '''Malignant''' | ||