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Difference between revisions of "Basal cell hyperplasia of the prostate"
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Basal cell hyperplasia of the prostate (view source)
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# | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Basal cell hyperplasia of prostate - very high mag.jpg | |||
| Width = | |||
| Caption = Basal cell hyperplasia of prostate. [[H&E stain]]. (WC) | |||
| Synonyms = | |||
| Micro = low power gland architecture near normal, glands usually ''not'' as small as cancer, usu. lack nuclear hyperchromasia, two cell populations (as in normal prostate glands), basal cells may have [[nucleoli]] | |||
| Subtypes = | |||
| LMDDx = urothelial metaplasia, [[prostate carcinoma]] | |||
| Stains = | |||
| IHC = basal presents (p63 +ve, CK34betaE12 +ve) | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Staging = | |||
| Site = [[prostate gland]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = none | |||
| Symptoms = none | |||
| Prevalence = common | |||
| Bloodwork = | |||
| Rads = none | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = incidental microscopic finding | |||
| ClinDDx = | |||
| Tx = none | |||
}} | |||
'''Basal cell hyperplasia of the prostate''', also known as '''basal cell hyperplasia''', is a benign change of the [[prostate gland]] that may be misdiagnosed as [[prostate carcinoma]]. | |||
==General== | |||
*Benign lesion that can be misdiagnosed as cancer.<ref name=pmid6195916>{{Cite journal | last1 = Cleary | first1 = KR. | last2 = Choi | first2 = HY. | last3 = Ayala | first3 = AG. | title = Basal cell hyperplasia of the prostate. | journal = Am J Clin Pathol | volume = 80 | issue = 6 | pages = 850-4 | month = Dec | year = 1983 | doi = | PMID = 6195916 }}</ref> | |||
==Microscopic== | |||
Features:<ref>URL: [http://pathologyoutlines.com/prostate.html#bch http://pathologyoutlines.com/prostate.html#bch]. Accessed on: 28 June 2010.</ref> | |||
*Low power gland architecture near normal.<ref>URL: [http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f1.html http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f1.html]. Accessed on: 28 June 2010.</ref><ref>URL: [http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f2.html http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f2.html]. Accessed on: 28 June 2010.</ref> | |||
**Glands ''not'' as small as cancer. | |||
**Folds in gland lumina. | |||
*No nuclear hyperchromasia. | |||
*Two cell populations (as in normal prostate glands). | |||
*Basal cells may have [[nucleoli]]. | |||
DDx: | |||
*[[High-grade prostatic intraepithelial neoplasia]] - has nuclear hyperchromasia, architecture usually different (micropapillary, tufted, cribriform or flat). | |||
*[[Prostatic adenocarcinoma]]. | |||
*[[Adenoid cystic/basal cell carcinoma of the prostate]] - for the adenoid cystic-like pattern of BCH.<ref name=pmid15371944>{{Cite journal | last1 = McKenney | first1 = JK. | last2 = Amin | first2 = MB. | last3 = Srigley | first3 = JR. | last4 = Jimenez | first4 = RE. | last5 = Ro | first5 = JY. | last6 = Grignon | first6 = DJ. | last7 = Young | first7 = RH. | title = Basal cell proliferations of the prostate other than usual basal cell hyperplasia: a clinicopathologic study of 23 cases, including four carcinomas, with a proposed classification. | journal = Am J Surg Pathol | volume = 28 | issue = 10 | pages = 1289-98 | month = Oct | year = 2004 | doi = | PMID = 15371944 }}</ref> | |||
*Urothelial metaplasia of the prostate - larger cells, cell borders seen. | |||
===Images=== | |||
<gallery> | |||
Image: Basal cell hyperplasia of prostate - intermed mag.jpg | BCH - intermed. mag. | |||
Image: Basal cell hyperplasia of prostate - high mag.jpg | BCH - high mag. | |||
Image: Basal cell hyperplasia of prostate - very high mag.jpg | BCH - very high mag. | |||
Image: Basal cell hyperplasia of prostate - alt - very high mag.jpg | BCH - very high mag. | |||
</gallery> | |||
====www==== | |||
*[http://webpathology.com/image.asp?case=18&n=1 Basal cell hyperplasia of the prostate (webpathology.com)]. | |||
==Sign out== | |||
*Usually not reported. | |||
==See also== | |||
*[[Prostate gland]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Genitourinary pathology]] | |||