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Difference between revisions of "Basal cell carcinoma"
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- DERMAL SCAR. | - DERMAL SCAR. | ||
- EXTENSIVE SOLAR ELASTOSIS. | - EXTENSIVE SOLAR ELASTOSIS. | ||
</pre> | |||
===Infiltrative BCC=== | |||
<pre> | |||
SKIN LESION, RIGHT EAR, SHAVE BIOPSY: | |||
- INFILTRATIVE BASAL CELL CARCINOMA WITH FOCAL SCLEROSIS, DEEP AND LATERAL | |||
MARGINS POSITIVE. | |||
- ACTINIC KERATOSIS. | |||
- ULCERATION. | |||
COMMENT: | |||
The tumour stains as follows: | |||
POSITIVE: CK34betaE12, Ber-EP4. | |||
NEGATIVE: S-100, EMA. | |||
</pre> | </pre> | ||
===Micro=== | ===Micro=== | ||
The sections show hair-bearing skin with nests of basaloid cells in the dermis. The basaloid nests have peripheral palisading of the nuclei, have numerous mitoses, and are surrounded by a myxoid stroma. The nests are well demarcated from the stroma and show focal clefting from the stroma. The margins are negative for basal cell carcinoma. | The sections show hair-bearing skin with nests of basaloid cells in the dermis. The basaloid nests have peripheral palisading of the nuclei, have numerous mitoses, and are surrounded by a myxoid stroma. The nests are well demarcated from the stroma and show focal clefting from the stroma. The margins are negative for basal cell carcinoma. | ||
====Infiltrative BCC==== | |||
The sections show ulcerated skin. In the dermis there are single atypical cells, small clusters of atypical cells and rows of atypical cells. The atypical cells have moderate grey cytoplasm, irregular nucleoli, and pale nuclei. Mitotic activity is present. The stroma is partially sclerotic. | |||
The epidermis (where present) has basal atypia and focal parakeratosis. | |||
The atypical lesion is present at the deep and lateral margins. | |||
==See also== | ==See also== | ||