Autopsy

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Autopsy is a part of pathology.

External exam

Is very important in the forensic context.

External exam findings are found in the forensic pathology article.

Internal exam

Is usually where the money is in non-forensic autopsies, i.e. hospital autopsies.

Spleen

Sugar-coated spleen

  • Properly referred to as hyaloserositis of the spleen.
  • Capsule of the spleen is white - resembles sugar-coating.
  • Importance: none - benign.

Liver

  • Portal vein patency.

Kidney

Size of the kidney - small kidneys are seen in chronic renal failure.

Nephrosclerosis

  • Flea-bitten appearance - seen in hypertension.[1]

ATN

  • ATN is difficult to prove on autopsy material.
  • Look for:
    • Heme-granular casts in the lumen.
    • Regenerative activity (mitoses).

Brain

  • One should saw through the skull completely, i.e. one should not "crack" the skull open with a chisel.
    • Cracking open the skull may result in artefactual fractures that are impossible to differentiate from antemortem fractures.
    • Cuts into the brain (from opening the skull) are not difficult to distinguish from antemortem injuries.

Weird stuff

  • Methylene blue, used for refractory shock,[2] turns organs green.[3]
  • Hyperviscosity syndrome - in leukemia.[4]

Normal organ mass

Caucasoid population of 684 adults:[5]

Men Women
Heart 365 +/- 71 g 312 +/- 78 g
Right lung 663 +/- 239 g 546 +/- 207 g
Left lung 583 +/- 216 g 467 +/- 174 g
Liver 1677 +/- 396 g 1475 +/- 362 g
Spleen 156 +/- 87 g 140 +/- 78 g
Right kidney 162 +/- 39 g 135 +/- 39 g
Left kidney 160 +/- 41 g 136 +/- 37 g

See also

References

  1. Ono, H.; Ono, Y. (Nov 1997). "Nephrosclerosis and hypertension.". Med Clin North Am 81 (6): 1273-88. PMID 9356598.
  2. Heemskerk, S.; van Haren, FM.; Foudraine, NA.; Peters, WH.; van der Hoeven, JG.; Russel, FG.; Masereeuw, R.; Pickkers, P. (Feb 2008). "Short-term beneficial effects of methylene blue on kidney damage in septic shock patients.". Intensive Care Med 34 (2): 350-4. doi:10.1007/s00134-007-0867-9. PMID 17926021.
  3. Tan, CD.; Rodriguez, ER.. "Blue dye, green heart.". Cardiovasc Pathol 19 (2): 125-6. doi:10.1016/j.carpath.2008.06.012. PMID 18703358.
  4. http://cat.inist.fr/?aModele=afficheN&cpsidt=18942659
  5. de la Grandmaison GL, Clairand I, Durigon M (June 2001). "Organ weight in 684 adult autopsies: new tables for a Caucasoid population". Forensic Sci. Int. 119 (2): 149–54. PMID 11376980.

External links