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Difference between revisions of "Anus"
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The '''anus''' occasionally shows-up on the pathologists desk. It sometimes comes with the rectum and [[colon]], as an abdominoperoneal resection (APR). | The '''anus''' occasionally shows-up on the pathologists desk. It sometimes comes with the rectum and [[colon]], as an abdominoperoneal resection (APR). | ||
=Benign disease= | |||
==Hidradenoma papilliferum== | |||
:See ''[[Hidradenoma papilliferum]]''. | |||
==Hemorrhoids== | |||
===General=== | |||
*Benign. | |||
Clinical features:<ref>{{Cite journal | last1 = Cazemier | first1 = M. | last2 = Felt-Bersma | first2 = RJ. | last3 = Cuesta | first3 = MA. | last4 = Mulder | first4 = CJ. | title = Elastic band ligation of hemorrhoids: flexible gastroscope or rigid proctoscope? | journal = World J Gastroenterol | volume = 13 | issue = 4 | pages = 585-7 | month = Jan | year = 2007 | doi = | PMID = 17278225 }}</ref> | |||
*Bright red blood per rectum (BRBPR). | |||
*Pain. | |||
*Itching. | |||
*Prolapse. | |||
===Gross=== | |||
Features:<ref name=Ref_GLP401>{{Ref GLP|401}}</ref> | |||
*Grey mucosa. | |||
*Pale or purple stroma. | |||
===Microscopic=== | |||
Features:<ref name=Ref_GLP401>{{Ref GLP|401}}</ref> | |||
*Polypoid lesion - epithelium on three sides: | |||
**Large dilated veins and thick-walled vessels +/- fibrin thrombi - '''key feature'''. | |||
**Edema. | |||
**Squamous epithelium +/- keratinization ''or'' columnar epithelium. | |||
DDx: | |||
*[[Fibroepithelial polyp]]. | |||
*Vascular lesions. | |||
**[[Kaposi sarcoma]]. | |||
**[[Angiosarcoma]]. | |||
Image: | |||
*[http://www.profimedia.si/picture/longitudinal-section-of-human-rectum-hemorrhoid-tissue/0039860546/ Hemorrhoids (profimedia.si)]. | |||
=Anal neoplasia= | =Anal neoplasia= | ||
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==Anal gland adenocarcinoma== | ==Anal gland adenocarcinoma== | ||
*Abbreviation ''AGA''. | |||
*[[AKA]] ''anal adenocarcinoma''. | *[[AKA]] ''anal adenocarcinoma''. | ||
===General=== | ===General=== | ||
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DDx: | DDx: | ||
*[[Rectal adenocarcinoma]]. | *[[Rectal adenocarcinoma]] - usu. CK7 -ve, CK20 +ve. | ||
*Mucinous adenocarcinoma - usu. CK7 +ve, CK20 +ve. | |||
Image: | Image: | ||
| Line 48: | Line 85: | ||
*p63 -ve. | *p63 -ve. | ||
*PSA -ve. | *PSA -ve. | ||
=See also= | =See also= | ||