Angiomyofibroblastoma

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Angiomyofibroblastoma is rare uncommon soft tissue lesion of the vulva.

General

Uncommon.

Clinical DDx:

Bartholin cyst.

Microscopic

Features:^[1]

Hypercellular zones and hypocellular edematous zones.
Small blood vessels (~20 micrometers) - no large blood vessels - key feature.
Myxoid stroma - key feature.
Small stellate cell/spindle cells without significant nuclear atypia.

DDx:

Aggressive angiomyxoma - less cellular, large blood vessels.

Images

www:

See also

Soft tissue lesions.

References

↑ Fletcher, CD.; Tsang, WY.; Fisher, C.; Lee, KC.; Chan, JK. (Apr 1992). "Angiomyofibroblastoma of the vulva. A benign neoplasm distinct from aggressive angiomyxoma.". Am J Surg Pathol 16 (4): 373-82. PMID 1314521.

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