Difference between revisions of "Angiolymphoid hyperplasia with eosinophilia"
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'''Angiolymphoid hyperplasia with eosinophilia''', abbreviated '''ALHE''', is a rare [[skin]] [[dermatopathology|pathology]]. | '''Angiolymphoid hyperplasia with eosinophilia''', abbreviated '''ALHE''', is a rare [[skin]] [[dermatopathology|pathology]]. It is also known as ''epithelioid [[hemangioma]]''.<ref name=Ref_Derm548>{{Ref Derm|548}}</ref> | ||
==General== | ==General== | ||
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*Hypothesized to be a precursor to lymphoma.<ref name=pmid18510751>{{Cite journal | last1 = Gonzalez-Cuyar | first1 = LF. | last2 = Tavora | first2 = F. | last3 = Zhao | first3 = XF. | last4 = Wang | first4 = G. | last5 = Auerbach | first5 = A. | last6 = Aguilera | first6 = N. | last7 = Burke | first7 = AP. | title = Angiolymphoid hyperplasia with eosinophilia developing in a patient with history of peripheral T-cell lymphoma: evidence for multicentric T-cell lymphoproliferative process. | journal = Diagn Pathol | volume = 3 | issue = | pages = 22 | month = | year = 2008 | doi = 10.1186/1746-1596-3-22 | PMID = 18510751 }}</ref> | *Hypothesized to be a precursor to lymphoma.<ref name=pmid18510751>{{Cite journal | last1 = Gonzalez-Cuyar | first1 = LF. | last2 = Tavora | first2 = F. | last3 = Zhao | first3 = XF. | last4 = Wang | first4 = G. | last5 = Auerbach | first5 = A. | last6 = Aguilera | first6 = N. | last7 = Burke | first7 = AP. | title = Angiolymphoid hyperplasia with eosinophilia developing in a patient with history of peripheral T-cell lymphoma: evidence for multicentric T-cell lymphoproliferative process. | journal = Diagn Pathol | volume = 3 | issue = | pages = 22 | month = | year = 2008 | doi = 10.1186/1746-1596-3-22 | PMID = 18510751 }}</ref> | ||
==Gross== | |||
*Location: usually head and neck.<ref name=pmid18510751/> | |||
*Skin papules ''or'' nodules.<ref name=pmid8733384>{{Cite journal | last1 = Bartralot | first1 = R. | last2 = Garcia-Patos | first2 = V. | last3 = Hueto | first3 = J. | last4 = Huguet | first4 = P. | last5 = Raspall | first5 = G. | last6 = Castells | first6 = A. | title = Angiolymphoid hyperplasia with eosinophilia affecting the oral mucosa: report of a case and a review of the literature. | journal = Br J Dermatol | volume = 134 | issue = 4 | pages = 744-8 | month = Apr | year = 1996 | doi = | PMID = 8733384 }}</ref> | *Skin papules ''or'' nodules.<ref name=pmid8733384>{{Cite journal | last1 = Bartralot | first1 = R. | last2 = Garcia-Patos | first2 = V. | last3 = Hueto | first3 = J. | last4 = Huguet | first4 = P. | last5 = Raspall | first5 = G. | last6 = Castells | first6 = A. | title = Angiolymphoid hyperplasia with eosinophilia affecting the oral mucosa: report of a case and a review of the literature. | journal = Br J Dermatol | volume = 134 | issue = 4 | pages = 744-8 | month = Apr | year = 1996 | doi = | PMID = 8733384 }}</ref> | ||
* | |||
Image: | |||
*[http://www.atlasdermatologico.com.br/ListaImagens/Angiolymphoid_Hyperplasia_With_Eosinophilia4.JPG ALHE (atlasdermatologico.com.br)]. | |||
==Microscopic== | ==Microscopic== | ||
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*[[Kaposi sarcoma]]. | *[[Kaposi sarcoma]]. | ||
*[[Lymphoma]]. | *[[Lymphoma]]. | ||
Image: | |||
*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20080802175600790 ALHE (surgicalpathologyatlas.com)]. | |||
==See also== | ==See also== | ||
Latest revision as of 16:33, 4 June 2013
Angiolymphoid hyperplasia with eosinophilia, abbreviated ALHE, is a rare skin pathology. It is also known as epithelioid hemangioma.[1]
General
- Similar to Kimura disease.[2]
- Very rare.
- Typical patient: Caucasian, woman.[2]
- Hypothesized to be a precursor to lymphoma.[3]
Gross
Image:
Microscopic
Features:[2]
- Marked vascular proliferation.
- Few lymphoid follicles.
- Moderate eosinophils.
Negative:
- No fibrosis.
DDx:
Image:
See also
References
- ↑ Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 548. ISBN 978-0443066542.
- ↑ 2.0 2.1 2.2 Zaraa, I.; Mlika, M.; Chouk, S.; Chelly, I.; Mokni, M.; Zitouna, M.; Osman, AB. (2011). "Angiolymphoid hyperplasia with eosinophilia: a study of 7 cases.". Dermatol Online J 17 (2): 1. PMID 21382284.
- ↑ 3.0 3.1 Gonzalez-Cuyar, LF.; Tavora, F.; Zhao, XF.; Wang, G.; Auerbach, A.; Aguilera, N.; Burke, AP. (2008). "Angiolymphoid hyperplasia with eosinophilia developing in a patient with history of peripheral T-cell lymphoma: evidence for multicentric T-cell lymphoproliferative process.". Diagn Pathol 3: 22. doi:10.1186/1746-1596-3-22. PMID 18510751.
- ↑ Bartralot, R.; Garcia-Patos, V.; Hueto, J.; Huguet, P.; Raspall, G.; Castells, A. (Apr 1996). "Angiolymphoid hyperplasia with eosinophilia affecting the oral mucosa: report of a case and a review of the literature.". Br J Dermatol 134 (4): 744-8. PMID 8733384.