Difference between revisions of "Angiodysplasia"

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Compatible with angiodysplasia -- low mag.jpg
| Width      =
| Caption    = Compatible with angiodysplasia. [[H&E stain]].
| Synonyms  =
| Micro      = dilated vessels in mucosa and submucosa
| Subtypes  =
| LMDDx      = prominent vessels
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Staging    =
| Site      =
| Assdx      =
| Syndromes  =
| Clinicalhx = older individuals
| Signs      = bleeding from rectum
| Symptoms  =
| Prevalence =
| Bloodwork  =
| Rads      =
| Endoscopy  = red lesion - typically right colon or cecum
| Prognosis  =
| Other      =
| ClinDDx    = Other causes of [[Colon#Bleeding|lower GI bleed]]
| Tx        =
}}
'''Angiodysplasia''' is a benign pathology of the large bowel.
'''Angiodysplasia''' is a benign pathology of the large bowel.


==General===
==General==
*Causes (lower) GI haemorrhage.
*[[Clinical diagnosis]].
*[[Colon#Bleeding|Cause of (lower) GI haemorrhage]].
*Generally, not a problem pathologists see.
*Generally, not a problem pathologists see.
*May be associated with [[aortic stenosis]]; known as ''Heyde syndrome''.<ref name=pmid19652242>{{cite journal |author=Hui YT, Lam WM, Fong NM, Yuen PK, Lam JT |title=Heyde's syndrome: diagnosis and management by the novel single-balloon enteroscopy |journal=Hong Kong Med J |volume=15 |issue=4 |pages=301–3 |year=2009 |month=August |pmid=19652242 |doi= |url=http://www.hkmj.org/abstracts/v15n4/301.htm}}</ref>
*May be associated with aortic stenosis; known as ''Heyde syndrome''.<ref name=pmid19652242>{{cite journal |author=Hui YT, Lam WM, Fong NM, Yuen PK, Lam JT |title=Heyde's syndrome: diagnosis and management by the novel single-balloon enteroscopy |journal=Hong Kong Med J |volume=15 |issue=4 |pages=301–3 |year=2009 |month=August |pmid=19652242 |doi= |url=http://www.hkmj.org/abstracts/v15n4/301.htm}}</ref>


Epidemiology:
Epidemiology:
Line 17: Line 50:
Note:
Note:
*[[Crohn's disease]] - may mimic angiodysplasia radiographically.<ref name=pmid3054852/>
*[[Crohn's disease]] - may mimic angiodysplasia radiographically.<ref name=pmid3054852/>
===Images===
<gallery>
Image:Argon plasma coagulation.jpg | Angiodysplasia - endoscopy. (WC/Grover)
</gallery>


==Microscopic==
==Microscopic==
Features:<ref name=pmid3054852>{{Cite journal  | last1 = Hemingway | first1 = AP. | title = Angiodysplasia: current concepts. | journal = Postgrad Med J | volume = 64 | issue = 750 | pages = 259-63 | month = Apr | year = 1988 | doi =  | PMID = 3054852 }}</ref>
Features:<ref name=pmid3054852>{{Cite journal  | last1 = Hemingway | first1 = AP. | title = Angiodysplasia: current concepts. | journal = Postgrad Med J | volume = 64 | issue = 750 | pages = 259-63 | month = Apr | year = 1988 | doi =  | PMID = 3054852 }}</ref>
*Dilated vessels in mucosa and submucosa.
*Dilated [[blood vessels]] in the mucosa and submucosa.
 
DDx:
*[[Crohn's disease]] - may be associated increase vascularity.
 
===Images===
<gallery>
Image: Compatible with angiodysplasia -- extremely low mag.jpg | AD - extremely low mag.
Image: Compatible with angiodysplasia -- very low mag.jpg | AD - very low mag.
Image: Compatible with angiodysplasia -- low mag.jpg | AD - low mag.
Image: Compatible with angiodysplasia -- intermed mag.jpg | AD - intermed. mag.
Image: Compatible with angiodysplasia - alt -- intermed mag.jpg | AD - intermed. mag.
Image: Compatible with angiodysplasia -- high mag.jpg | AD - high mag.
</gallery>


==See also==
==See also==

Latest revision as of 03:10, 23 November 2016

Angiodysplasia
Diagnosis in short

Compatible with angiodysplasia. H&E stain.

LM dilated vessels in mucosa and submucosa
LM DDx prominent vessels
Clinical history older individuals
Signs bleeding from rectum
Endoscopy red lesion - typically right colon or cecum
Clin. DDx Other causes of lower GI bleed

Angiodysplasia is a benign pathology of the large bowel.

General

Epidemiology:

  • Older people.

Etiology:

  • Thought to be caused by the higher wall tension of cecum (due to larger diameter) and result from (intermittent) venous occlusion/focal dilation of vessels.[2]

Gross

  • Cecum - classic location.

Note:

Images

Microscopic

Features:[3]

DDx:

Images

See also

References

  1. Hui YT, Lam WM, Fong NM, Yuen PK, Lam JT (August 2009). "Heyde's syndrome: diagnosis and management by the novel single-balloon enteroscopy". Hong Kong Med J 15 (4): 301–3. PMID 19652242. http://www.hkmj.org/abstracts/v15n4/301.htm.
  2. Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease (7th ed.). St. Louis, Mo: Elsevier Saunders. pp. 854. ISBN 0-7216-0187-1.
  3. 3.0 3.1 Hemingway, AP. (Apr 1988). "Angiodysplasia: current concepts.". Postgrad Med J 64 (750): 259-63. PMID 3054852.