Difference between revisions of "An introduction to head and neck pathology"

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An introduction to head and neck pathology (view source)

Revision as of 02:44, 14 September 2010

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split-out odontogenic tumours and cysts
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Image: [http://www.lmp.ualberta.ca/resources/pathoimages/Images-C/000p039r.jpg Craniopharyngioma - micrograph (lmp.ualbera.ca)].
Image: [http://www.lmp.ualberta.ca/resources/pathoimages/Images-C/000p039r.jpg Craniopharyngioma - micrograph (lmp.ualbera.ca)].


==Keratocystic odontogenic tumour==
==Odontogenic tumours and cysts==
===General===
{{main|Odontogenic tumours and cysts}}
*Used to be known as ''odontogenic keratocyst''.<ref name=pmid18353202>{{Cite journal  | last1 = Madras | first1 = J. | last2 = Lapointe | first2 = H. | title = Keratocystic odontogenic tumour: reclassification of the odontogenic keratocyst from cyst to tumour. | journal = J Can Dent Assoc | volume = 74 | issue = 2 | pages = 165-165h | month = Mar | year = 2008 | doi =  | PMID = 18353202 }}
</ref>
*May be associated with ''[[nevoid basal cell carcinoma syndrome]]''.


===Clinical===
This is a rather large topic and dealt with in a separate article.
Features:<ref name=pmid17928730>{{Cite journal  | last1 = Habibi | first1 = A. | last2 = Saghravanian | first2 = N. | last3 = Habibi | first3 = M. | last4 = Mellati | first4 = E. | last5 = Habibi | first5 = M. | title = Keratocystic odontogenic tumor: a 10-year retrospective study of 83 cases in an Iranian population. | journal = J Oral Sci | volume = 49 | issue = 3 | pages = 229-35 | month = Sep | year = 2007 | doi =  | PMID = 17928730 }}</ref>
*Most common presentation: swelling.
*Location: usually mandible.
*May mimic ameloblastoma radiologically.


===Microscopic===
It includes:
Features: <ref>Thompson LDR. Head and neck pathology - (Foundations in diagnostic pathology). Goldblum JR, Ed.. Churchill Livingstone. 2006. ISBN 0-443-06960-3.</ref>
*Keratocystic odontogenic tumour.
* Stratified epithelium resembling squamous epithelium -- but:
*Ameloblastoma.
** Lacks [[rete ridges]].
** Artefactual separation of epithelium from the basement membrane.
 
DDx:
*Odontogenic cyst.
 
Images:
*[http://commons.wikimedia.org/wiki/File:Keratocystic_odontogenic_tumour1.jpg KOT (WC)].
*[http://commons.wikimedia.org/wiki/File:Keratocystic_odontogenic_tumour2.jpg KOT - showing artefactual separation of epithelium (WC)].
 
==Ameloblastoma==
===General===
*Osteous lesion.
 
===Microscopic===
Features:<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970616-7 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970616-7]. Accessed on: March 9, 2010.</ref>
*Stellate reticulum - star-shaped cells, found in a developing tooth.<ref>URL: [http://en.wikipedia.org/wiki/Stellate_reticulum http://en.wikipedia.org/wiki/Stellate_reticulum]. Accessed on: March 9, 2010.</ref>
*Tall columnar cells.
**Nuclei distant from the basement membrane (reverse polarization of the nuclei).
*+/-Giant cells.
 
Images:
*[http://www.estomatologia.com.br/diagnosticos_det2.asp?cod_diag=12 Ameloblastoma - several images (estomatologia.com.br)].
*[http://www.cytochemistry.net/microanatomy/digestive/devtooth9.jpg Stellate reticulum (cytochemistry.net)].


==Nasal polyps==
==Nasal polyps==
Michael
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