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Immunostain in short
Abbreviation AFP
Subspeciality genitourinary pathology, gastrointestinal pathology
Positive yolk sac tumour, hepatocellular carcinoma
Other common serum tumour marker

Alpha-fetoprotein, abbreviated AFP, is plasma protein seen in fetal life and produced by various tumours.

Elevated AFP - classic causes


See also


  1. 1.0 1.1 Ip, S.; Schaeffer, DF.; Yoshida, EM.; Kwan, WP. (Apr 2015). "Alpha Fetoprotein-Secreting Gastric Cancer in the Setting of Chronic Hepatitis B: The Role of Endoscopy.". ACG Case Rep J 2 (3): 152-4. doi:10.14309/crj.2015.38. PMID 26157947.
  2. Anzai, H.; Kazama, S.; Kiyomatsu, T.; Nishikawa, T.; Tanaka, T.; Tanaka, J.; Hata, K.; Kawai, K. et al. (2015). "Alpha-fetoprotein-producing early rectal carcinoma: a rare case report and review.". World J Surg Oncol 13: 180. doi:10.1186/s12957-015-0590-x. PMID 25962419.
  3. Tatli AM, Urakci Z, Kalender ME, Arslan H, Tastekin D, Kaplan MA (2015). "Alpha-fetoprotein (AFP) elevation gastric adenocarcinoma and importance of AFP change in tumor response evaluation". Asian Pac J Cancer Prev 16 (5): 2003–7. doi:10.7314/apjcp.2015.16.5.2003. PMID 25773802.