Difference between revisions of "ALK translocation renal cell carcinoma"

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==Microscopic==
==Microscopic==
Features:
Features:
*Mix of morphologies - rhabdoid, sarcomatoid, "[[unclassified renal cell carcinoma]]", [[papillary renal cell carcinoma]].
*Mix of morphologies - including rhabdoid change, sarcomatoid change, "[[unclassified renal cell carcinoma]]", [[papillary renal cell carcinoma]].


DDx:
DDx:

Revision as of 17:56, 17 March 2019

ALK translocation renal cell carcinoma is a proposed entity within the Vancouver modification of the 2004 WHO classification of renal neoplasia.[1]

General

Microscopic

Features:

DDx:

IHC

See also

References

  1. Srigley, JR.; Delahunt, B.; Eble, JN.; Egevad, L.; Epstein, JI.; Grignon, D.; Hes, O.; Moch, H. et al. (Oct 2013). "The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia.". Am J Surg Pathol 37 (10): 1469-89. doi:10.1097/PAS.0b013e318299f2d1. PMID 24025519.
  2. Mariño-Enríquez, A.; Ou, WB.; Weldon, CB.; Fletcher, JA.; Pérez-Atayde, AR. (Mar 2011). "ALK rearrangement in sickle cell trait-associated renal medullary carcinoma.". Genes Chromosomes Cancer 50 (3): 146-53. doi:10.1002/gcc.20839. PMID 21213368.
  3. 3.0 3.1 Pal, SK.; Bergerot, P.; Dizman, N.; Bergerot, C.; Adashek, J.; Madison, R.; Chung, JH.; Ali, SM. et al. (07 2018). "Responses to Alectinib in ALK-rearranged Papillary Renal Cell Carcinoma.". Eur Urol 74 (1): 124-128. doi:10.1016/j.eururo.2018.03.032. PMID 29685646.