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Allograft biopsy categories (Banff 97):[1]
Type
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Key morphologic finding
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Normal
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no inflammation
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Suspicious for acute rejection
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focal mild tubulitis (1-4 mononuclear cells/tubular cross section)
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Acute/active rejection
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tubulitis (>4 mononuclear cells/tubular cross section); see separate table for grading
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Chronic/sclerosing allograft nephropathy
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interstitial fibrosis and tubular atrophy; see separate table for grading
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Type
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Key morphologic finding
Acute/active rejection
Acute/active rejection in allograft biopsies (Banff 97):[1]
Grade
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Key morphologic finding
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IA
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4< mononuclear cell/tubular cross section or 10 tubular cells <10; >25% of parenchyma
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IB
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>10 mononuclear cell/tubular cross section or 10 tubular cells; >25% of parenchyma
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IIA
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mild-to-moderate intimal arteritis; <=25% of luminal area
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IIB
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severe intimal arteritis; >25% of luminal area
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III
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transmural arteritis and/or fibrinoid necrosis
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- ↑ 1.0 1.1 Fogo, Agnes B.; Kashgarian, Michael (2005). Diagnostic Atlas of Renal Pathology: A Companion to Brenner and Rector's The Kidney 7E (1st ed.). Saunders. pp. 400. ISBN 978-1416028710.
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