Vas deferens
The vas deferens is not seen commonly.
Vasitis nodosa
General
- Classically develops post-vasovasostomy (vasectomy reversal).[1]
- Seen in association with other surgical procedures.
- May be seen in the context of infertility (without prior vasectomy).
- Some similarity to salpingitis isthmica nodosa.
Gross
- Mass.
Microscopic
Features:[1]
- Tubules in wall of vas deferens.
- Lined by columnar/cuboidal epithelium.
- May have mitotic activity.
- Nucleoli.
- Contain sperm - small, dark staining, teardrop-shaped (~1 micrometer) - key feature.
- Lined by columnar/cuboidal epithelium.
- +/-Sperm granulomas.
- Histocytes - abundant foamy cytoplasm.
- Sperm - small, dark staining, teardrop-shaped (~1 micrometer).
Notes:
- Can be confused with prostatic adenocarcinoma:[2]
- May "invade" vascular spaces - associated with elastosis (breakdown of elastic fibres[3]).
Image:
See also
References
- ↑ 1.0 1.1 Hirschowitz, L.; Rode, J.; Guillebaud, J.; Bounds, W.; Moss, E. (Apr 1988). "Vasitis nodosa and associated clinical findings.". J Clin Pathol 41 (4): 419-23. PMC 1141468. PMID 3366928. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1141468/.
- ↑ Balogh, K.; Travis, WD. (Apr 1985). "Benign vascular invasion in vasitis nodosa.". Am J Clin Pathol 83 (4): 426-30. PMID 3984936.
- ↑ URL: http://medical-dictionary.thefreedictionary.com/elastosis. Accessed on: 26 September 2011.