Vas deferens

The vas deferens is not seen commonly.

Vasitis nodosa

Classically develops post-vasovasostomy (vasectomy reversal).^[1]
- Seen in association with other surgical procedures.
- May be seen in the context of infertility (without prior vasectomy).
Some similarity to salpingitis isthmica nodosa.

Features:^[1]

Tubules in wall of vas deferens.
- Lined by columnar/cuboidal epithelium.
  - May have mitotic activity.
  - Nucleoli.
+/-Sperm granulomas.
- Histocytes - abundant foamy cytoplasm.
- Sperm - small black dots (~1 micrometer).

Notes:

Can be confused with prostatic adenocarcinoma:^[2]
- May "invade" vascular spaces - associated with elastosis (breakdown of elastic fibres^[3]).

Image:

↑ ^1.0 ^1.1 Hirschowitz, L.; Rode, J.; Guillebaud, J.; Bounds, W.; Moss, E. (Apr 1988). "Vasitis nodosa and associated clinical findings.". J Clin Pathol 41 (4): 419-23. PMC 1141468. PMID 3366928. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1141468/.
↑ Balogh, K.; Travis, WD. (Apr 1985). "Benign vascular invasion in vasitis nodosa.". Am J Clin Pathol 83 (4): 426-30. PMID 3984936.
↑ URL: http://medical-dictionary.thefreedictionary.com/elastosis. Accessed on: 26 September 2011.