Dermal cysts
Dermal cysts are common in dermatopathology. Dermatopathologists can diagnose 'em.
Cysts
Common types:[1]
- Epidermal cyst (sebaceous cyst) -- most common.
- Pilar (trichilemmal) cyst.
- Dermoid cyst.
- Ganglion cyst.
- Milicem.
Epidermal necrosis
- This may be cystic. It is covered in the epidermal necrosis article, which covers erythema multiforme, Steven-Johnson syndrome and toxic epidermal necrolysis.
Venous lake
- Dilated vein.
Microscopic
Features:[2]
- Lined by endothelium.
- Blood in lumen.
- +/-Fibrin in lumen.
DDx:
- Angiokeratoma.
- Ectatic superficial dermal vessels.
- Irregular acanthosis.
- Longer rete ridges.
Epidermal inclusion cyst
- AKA epidermal cyst.
General
- Very common.
Microscopic
Features:
- Cyst lining has a granular layer - key feature.[3]
- Trapped collagen bundles at edge of lesion with surrounded by fibroblasts.
- Keratin.
Image:
DDx:
- Dermatofibrosarcoma - if lesion is large.
- Pilar cyst - no granular layer.
Pilar cyst
- AKA trichilemmal cyst.
General
- Very common.
Microscopic
Features:
- Keratin.
- Cyst lining has no granular layer - key feature.
- Trapped collagen bundles at edge of lesion with surrounded by fibroblasts.
DDx:
- Epidermal cyst - has a granular layer.
Steatocystoma
General
- Benign.
- Typically adults.
- Usually on the trunk.
Microscopic
Features:[4]
- Cyst lined by squamous epithelium with:
- Corrugated eosinophilic lining - key feature.
- Similar appearance to compact keratin (hyperkeratosis).
- No granular cell layer.
- Corrugated eosinophilic lining - key feature.
See also
References
- ↑ TN07 D5
- ↑ Weedon's Skin Pathology. 3rd Ed. P.895.
- ↑ URL: http://emedicine.medscape.com/article/1058907-diagnosis. Accessed on: 18 March 2011.
- ↑ Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 312. ISBN 978-0443066542.