Hepatitis B
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Hepatitis B is a relatively common medical liver disease caused by the hepatitis B virus.
General
- May lead to hepatocellular carcinoma without cirrhosis.
- High prevalence.
- Diagnosis is by serology - details of serologic testing are in the medical liver disease article.
- A vaccination is available and done routinely in a many jurisdictions.[1]
Associated pathology:
Microscopic
Features:
- Lobular inflammation - this is non-specific finding.
- Hepatocyte necrosis:
- Necrotic hepatocytes look a lot like neutrophils - however:
- Cytoplasm is more pink.
- Round apoptotic bodies.
- Necrotic hepatocytes look a lot like neutrophils - however:
- Hepatocyte necrosis:
- Ground glass hepatocytes - important.
DDx:
Image
IHC
- Hepatitis B +ve.
See also
References
- ↑ Leuridan, E.; Van Damme, P. (Jul 2011). "Hepatitis B and the need for a booster dose.". Clin Infect Dis 53 (1): 68-75. doi:10.1093/cid/cir270. PMID 21653306.