Adenoid cystic carcinoma of the breast
Adenoid cystic carcinoma of the breast is a rare type of breast cancer that is similar to a relatively common tumour of the salivary gland.
General
- Like tumour of the salivary gland.
- Very rare <0.1% of breast malignancies.[1]
- Good prognosis.[1]
Microscopic
- See: Adenoid cystic carcinoma article.
DDx:
- Cribriform DCIS.
- Invasive cribriform carcinoma.
- Collagenous spherulosis.
Images
Breast Adenoid Cystic Carcinoma - low power (SKB)
Breast Adenoid Cystic Carcinoma - medium power (SKB)
Breast Adenoid Cystic Carcinoma - medium power (SKB)
Breast Adenoid Cystic Carcinoma - medium power (SKB)
Breast Adenoid Cystic Carcinoma - medium power (SKB)
Breast Adenoid Cystic Carcinoma - medium power (SKB)
Breast Adenoid Cystic Carcinoma - medium power (SKB)
Breast Adenoid Cystic Carcinoma - high power (SKB)
Breast Adenoid Cystic Carcinoma - high power (SKB)
Breast Adenoid Cystic Carcinoma - high power (SKB)
Breast Adenoid Cystic Carcinoma - high power (SKB)
Breast - Adenoid Cystic Carcinoma - Solid Type - Low power (SKB)
Breast - Adenoid Cystic Carcinoma - Solid Type - medium power - Aggregates of basaloid cells without tubule or cyst formation. (SKB)
Breast - Adenoid Cystic Carcinoma - Solid Type - High power (SKB)
Breast Adenoid Cystic Carcinoma - Solid Type - high power (SKB)
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IHC
- One of the 'good prognosis' triple negative breast cancers - ER, PR and HER2 negative.[2]
- Basal-like breast cancer - p63 and CK5/6 positive.[2]
CD117 positive[2]
Other Resources
Pathology Outlines [1]
See also
References
- ↑ 1.0 1.1 Boujelbene, N.; Khabir, A.; Boujelbene, N.; Jeanneret Sozzi, W.; Mirimanoff, RO.; Khanfir, K. (Dec 2011). "Clinical review - Breast adenoid cystic carcinoma.". Breast. doi:10.1016/j.breast.2011.11.006. PMID 22154460.
- ↑ 2.0 2.1 2.2 Azoulay, S.; Laé, M.; Fréneaux, P.; Merle, S.; Al Ghuzlan, A.; Chnecker, C.; Rosty, C.; Klijanienko, J. et al. (Dec 2005). "KIT is highly expressed in adenoid cystic carcinoma of the breast, a basal-like carcinoma associated with a favorable outcome.". Mod Pathol 18 (12): 1623-31. doi:10.1038/modpathol.3800483. PMID 16258515.