Bullous diseases

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Bullous disease happens. Dermatopathologists help diagnose it.

DDx of bullous disease:[1]

  • Bullous pemphigoid.
  • Pemphigus vulgaris.
  • Porphyria cutanea tarda.
  • Dermatitis herpetiformis.
  • Epidermolysis bullosa.

Bullous pemphigoid

Epidemiology

  • Old people (60-80 year olds).

Pemphigus vulgaris

Classic presentation

  • Mouth lesions.
  • Non-pruritic.

Treatment

  • Prednisone then steroid sparing agent.

Epidemiology

DDx: Hailey-Hailey disease.

Dermatitis herpetiformis

Assoc. with celiac sprue.

Porphyria cutanea tarda

Etiology

  • Genetic, autosomal dominant.

Appearance

  • Vesicles/bullae in photoexposed areas subjected to trauma.

Associations

Medications/Substances:

Non-infection chronic conditions:

Infections:

Treatment

  • d/c aggravating substances (listed above), phlebotomy, hydroxychloroquine if phlebotomy contraindicated.

Epidermolysis bullosa

  • Inherited, bullae & erosions from slight mechanical trauma.

See also

References

  1. TN07 D21-3.