Astrocytoma
Revision as of 16:38, 13 January 2011 by Michael (talk | contribs) (create -- split-out from CNS tumours)
An astrocytoma is a neoplasm derived from an astrocyte. Astrocytomas are common. This article deals with, among other things, rare astrocytomas. An overview of CNS tumours is found in the CNS tumours article.
Glioblastoma
Gliosarcoma
General
- Considered to be a variant of glioblastoma by WHO.[1]
- Rare ~ 200 cases reported in the literature.[1]
- Definition: gliosarcoma = glioblastoma + sarcomatous component.[2]
- Usual location (like glioblastoma): temporal lobe.
Microscopic
Features:
- Glioblastoma.
- Sarcomatous component (one of the following):[1][2]
- Fibroblastic.
- Cartilaginous.
- Osseous.
- Smooth muscle.
- Striated muscle.
- Adipocyte.
Image: Gliosarcoma - elastic von Gieson (WC).
See also
References
- ↑ 1.0 1.1 1.2 Han SJ, Yang I, Tihan T, Prados MD, Parsa AT (February 2010). "Primary gliosarcoma: key clinical and pathologic distinctions from glioblastoma with implications as a unique oncologic entity". J. Neurooncol. 96 (3): 313–20. doi:10.1007/s11060-009-9973-6. PMC 2808523. PMID 19618114. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808523/.
- ↑ 2.0 2.1 Ayadi L, Charfi S, Khabir A, et al. (March 2010). "[Cerebral gliosarcoma: clinico-pathologic study of 8 cases]" (in French). Tunis Med 88 (3): 142–6. PMID 20415184.