Cystitis cystica

Cystitis cystica is a common inflammatory process of the urinary bladder with cyst formation.

General

• Benign.
• Can be thought of as von Brunn nests with cystic change.
• Called ureteritis cystica if it happens in a ureter.
  • There is also a urethritis cystica - seen in the urethra.

Microscopic

Features:

• Nests of urothelium within the lamina propria with cyst formation, i.e. lumens are present.

Note:

• Nests should not extend into the muscularis propria.

DDx:

• Nested urothelial carcinoma.

Image:

• Cystitis cystica (webpathology.com).

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URINARY BLADDER, BIOPSY:
- CYSTITIS CYSTICA.
- NEGATIVE FOR MALIGNANCY.

URINARY BLADDER, TRANSURETHRAL RESECTION:
- CYSTITIS CYSTICA ET GLANDULARIS, FOCALLY WITH LARGE THIN-WALLED CYSTS.
- PROMINENT BENIGN DILATED SUPERFICIAL BLOOD VESSELS, FOCAL.
- NEGATIVE FOR MALIGNANCY.

URINARY BLADDER (TRIGONE), TRANSURETHRAL BIOPSY:
- SMALL POLYPOID FRAGMENT OF UROTHELIUM CONSISTENT WITH CYSTITIS CYSTICA.
- NO SQUAMOUS METAPLASTIC CHANGE IDENTIFIED.
- NO EVIDENCE OF MALIGNANCY.

Micro

The sections show a small fragment of urothelial mucosa with small urothelial nests that are focally cystic. The nests are well-circumscribed and approximately of equal size. Adjacent to the nests is a small cluster of bland appearing lymphocytes.

No exophytic component is identified. No papillary structures are apparent. The cytomorphology of the urothelium is bland and no mitotic activity is readily apparent.

See also

• Urothelium.