Seminal vesicles
The seminal vesicles are a pair of organs closely associated with the prostate gland that fluid to the ejaculate. They are seen attached to prostatectomy specimens.
General
- Seen in radical prostatectomies and occasionally in core biopsies.
- Very rarely a site of a primary cancer.
Microscopic
- Fern-like architecture - epithelial component clustered closely, looks like it connects.
- Epithelium surrounded by a thick layer of muscle (>10 cells across ~80 microns).
- Lipofuscin (coarse cytoplasmic yellow granules approximately 1-2 micrometers) - key feature.
- Nucleoli - common.
- Nuclear inclusions - common.[1]
Notes:
- The ejaculatory ducts have the same epithelium as the seminal vesicles.[2]
Images
SV - showing fern-like architecture. (WC/Nephron)
SV - looking vaguely like to prostate adenocarcinoma. (WC/Nephron)
SV - looks a bit like prostate but lumina too big. (WC/Nephron)
www:
IHC
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B. PROSTATE, RIGHT MEDIAL SUPERIOR, BIOPSY: - BENIGN PROSTATE TISSUE. - BENIGN SEMINAL VESICLE/EJACULATORY DUCT.
See also
References
- ↑ URL: http://surgpathcriteria.stanford.edu/prostate/adenocarcinoma/benign-vs-carcinoma.html. Accessed on: 10 January 2013.
- ↑ Leroy X, Ballereau C, Villers A, et al. (April 2003). "MUC6 is a marker of seminal vesicle-ejaculatory duct epithelium and is useful for the differential diagnosis with prostate adenocarcinoma". Am. J. Surg. Pathol. 27 (4): 519–21. PMID 12657938.
- ↑ Itami, Y.; Nagai, Y.; Kobayashi, Y.; Shimizu, N.; Yamamoto, Y.; Minami, T.; Hayashi, T.; Nozawa, M. et al. (Jul 2012). "[A case of prostatic cancer with a low PSA level accompanied with cystic formation requiring differentiation from adenocarcinoma of the seminal vesicle].". Hinyokika Kiyo 58 (7): 349-53. PMID 22895132.
- ↑ 4.0 4.1 Tarján, M.; Ottlecz, I.; Tot, T. (Jan 2009). "Primary adenocarcinoma of the seminal vesicle.". Indian J Urol 25 (1): 143-5. doi:10.4103/0970-1591.45557. PMID 19468449.
- ↑ 5.0 5.1 5.2 5.3 Terada, T. (2011). "Monstrous epithelial cell clusters in the seminal vesicle.". Int J Clin Exp Pathol 4 (7): 727-30. PMID 22076175.