Hibernoma

Hibernoma is an uncommon tumour of brown fat. It is an adipocytic tumour.

General

• Consists of brown fat (present in the infants to generate heat).
• Benign.
• Usually asymptomatic.

Epidemiology:

• Young adults.

Gross

• Well-circumscribed.
• Lobulated and light-brown on sectioning.

Microscopic

Features:

• Large polygonal/oval cells:
  • Nucleus - central & small.
    • Nucleoli typically prominent.
  • Cytoplasm - multivacuolated, oval, eosinophilic, granular.
• +/-Prominent blood vessels, central.

DDx:

• Reaction to silicone implant.

Image

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  Hibernoma - high mag. (WC)

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  Hibernoma - intermed mag. (WC)

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  Hibernoma - low mag. (WC)

See also

• Adipocytic tumours.
• Lipoma.