Splenectomy grossing

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Splenectomy grossing deals with the cut-up of spleen specimens.

Introduction

The spleen is typically removed as it is enlarged (splenomegaly) and/or a source of bleeding.

It may be removed in the context of a hematological disorder, such as idiopathic thrombocytopenic purpura.[1] If a hematological disorder is suspected, tissue should be sent for flow cytometry.

Specimen opening

  • Weight specimen.
  • Cut for fixation.
  • Tissue for flow cytometry - if applicable.

Protocol

  • Weight: ___ grams.
  • Dimensions: ___ x ___ x ___ cm.
  • External surface: [ smooth, negative for lesions, negative for lacerations / adhesions / lacerations / other ___ ].
  • Cut surface - colour: [ brown / dark red colour ].
  • Lesion(s): number of lesions, size ___ cm, location [ periphery/central ], colour, consistency [ firm/soft ].
  • Lymph node(s): [ present - number ___, size ___ cm / absent ].

Sections:

  • Any lesions - at least representative.
  • Uninvolved spleen - 3 to 5 sections.
  • Lymph node(s).

Protocol notes

Staging

Alternate approaches

See also

Related protocols

References

  1. Jankulovski, N.; Antovic, S.; Kuzmanovska, B.; Mitevski, A. (2014). "Splenectomy for haematological disorders.". Pril (Makedon Akad Nauk Umet Odd Med Nauki) 35 (1): 181-7. PMID 24798604.