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Difference between revisions of "Medical liver disease"
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Medical liver disease (view source)
Revision as of 02:33, 25 November 2011
, 02:33, 25 November 2011→Vanishing bile duct syndrome: more
(→Drug toxicity: more) |
(→Vanishing bile duct syndrome: more) |
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=Other= | =Other= | ||
==Vanishing bile duct syndrome== | ==Vanishing bile duct syndrome== | ||
*[[AKA]] ''bile duct loss'', [[AKA]] ''ductopenia''.<ref name=pmid11521176/> | |||
===General=== | ===General=== | ||
*Fatal. | *Fatal. | ||
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*[[GVHD]].<ref name=pmid7994249>{{Cite journal | last1 = Yeh | first1 = KH. | last2 = Hsieh | first2 = HC. | last3 = Tang | first3 = JL. | last4 = Lin | first4 = MT. | last5 = Yang | first5 = CH. | last6 = Chen | first6 = YC. | title = Severe isolated acute hepatic graft-versus-host disease with vanishing bile duct syndrome. | journal = Bone Marrow Transplant | volume = 14 | issue = 2 | pages = 319-21 | month = Aug | year = 1994 | doi = | PMID = 7994249 }}</ref> | *[[GVHD]].<ref name=pmid7994249>{{Cite journal | last1 = Yeh | first1 = KH. | last2 = Hsieh | first2 = HC. | last3 = Tang | first3 = JL. | last4 = Lin | first4 = MT. | last5 = Yang | first5 = CH. | last6 = Chen | first6 = YC. | title = Severe isolated acute hepatic graft-versus-host disease with vanishing bile duct syndrome. | journal = Bone Marrow Transplant | volume = 14 | issue = 2 | pages = 319-21 | month = Aug | year = 1994 | doi = | PMID = 7994249 }}</ref> | ||
*Drugs.<ref name=pmid11352118>{{Cite journal | last1 = Chitturi | first1 = S. | last2 = Farrell | first2 = GC. | title = Drug-induced cholestasis. | journal = Semin Gastrointest Dis | volume = 12 | issue = 2 | pages = 113-24 | month = Apr | year = 2001 | doi = | PMID = 11352118 }}</ref> | *Drugs.<ref name=pmid11352118>{{Cite journal | last1 = Chitturi | first1 = S. | last2 = Farrell | first2 = GC. | title = Drug-induced cholestasis. | journal = Semin Gastrointest Dis | volume = 12 | issue = 2 | pages = 113-24 | month = Apr | year = 2001 | doi = | PMID = 11352118 }}</ref> | ||
*Chronic rejection.<ref name=pmid11521176>{{Cite journal | last1 = Inomata | first1 = Y. | last2 = Tanaka | first2 = K. | title = Pathogenesis and treatment of bile duct loss after liver transplantation. | journal = J Hepatobiliary Pancreat Surg | volume = 8 | issue = 4 | pages = 316-22 | month = | year = 2001 | doi = 10.1007/s0053410080316 | PMID = 11521176 }}</ref> | |||
===Microscopic=== | ===Microscopic=== | ||
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*Loss of intrahepatitic bile ducts - '''key feature'''. | *Loss of intrahepatitic bile ducts - '''key feature'''. | ||
*Cholestasis. | *Cholestasis. | ||
Note: | |||
*May occur without fibrosis and inflammation; thus, can be easy to miss. | |||
===IHC=== | ===IHC=== | ||