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Difference between revisions of "Bullous diseases"
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→Epidermolysis bullosa: more
(→Suprabasilar bullous disorders: +memory device) |
(→Epidermolysis bullosa: more) |
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Images: | Images: | ||
*[http://www.dermpedia.org/files/images/Image1_4.jpg Subepidermal blistering with thick vessels (dermpedia.org)]. | *[http://www.dermpedia.org/files/images/Image1_4.jpg Subepidermal blistering with thick vessels (dermpedia.org)]. | ||
==Epidermolysis bullosa acquisita== | |||
*Abbreviated ''EBA'' | |||
===General=== | |||
*Autoimmune disease. | |||
**Antibodies to collagen type VII.<ref>URL: [http://emedicine.medscape.com/article/1063083-overview http://emedicine.medscape.com/article/1063083-overview]. Accessed on: 25 September 2011.</ref> | |||
===Microscopic=== | |||
Features: | |||
*Subepidermal bullae. | |||
==Epidermolysis bullosa== | ==Epidermolysis bullosa== | ||
* | ===General=== | ||
*A group of inherited, bullous disorders. | |||
*Bullae form due to slight mechanical trauma. | |||
Three major groupings:<ref>URL: [http://emedicine.medscape.com/article/1062939-overview http://emedicine.medscape.com/article/1062939-overview]. Accessed on: 25 September 2011.</ref> | |||
#Epidermolysis bullosa simplex (intraepidermal disease). | |||
#Junctional epidermolysis bullosa (separation at DE junction; specifically central portion (lamina lucida)). | |||
#Dystrophic epidermolysis bullosa (separation at DE junction; specifically deep to lamina densa). | |||
===Microscopic=== | |||
Depends on subtype - either intraepidermal ''or'' subepidermal. | |||
==Grover disease== | ==Grover disease== | ||