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Difference between revisions of "Kidney tumours"
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→Chromophobe RCC
(→IHC: more) |
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Notes: | Notes: | ||
#May have [[psammoma bodies]]. | |||
#May appear similar to oncotyoma -- particularily the eosinophilic variant. | |||
#*A comparison based on histomorphology: ''[[Kidney_tumours#Tabular_comparison_of_oncocytoma_and_chromophobe_RCC|Tabular comparison between ChRCC & oncocytoma]]''. | |||
#**No perinuclear clearing in oncocytoma. | |||
Image: [http://commons.wikimedia.org/wiki/File:Oncocytic_chromophobe_rcc_high_mag.jpg Oncocytic chromophobe RCC (WC)]. | Image: [http://commons.wikimedia.org/wiki/File:Oncocytic_chromophobe_rcc_high_mag.jpg Oncocytic chromophobe RCC (WC)]. | ||
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DDx: | DDx: | ||
*May appear similar to oncotyoma -- particularily the eosinophilic variant. | *May appear similar to oncotyoma -- particularily the eosinophilic variant. | ||
**IHC may be useful to differentiate (CK7: oncocytoma = cytoplasm +ve, chromophobe = cell membrane +ve). | **IHC may be useful to differentiate (CK7: oncocytoma = cytoplasm +ve, chromophobe = cell membrane +ve). | ||
*Classic ChRCC may be challenging to differentiate from clear cell RCC. | *Classic ChRCC may be challenging to differentiate from clear cell RCC. | ||