Difference between revisions of "Kidney tumours"

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15 bytes added ,  03:21, 7 September 2011
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*Well-circumscribed.
*Well-circumscribed.


===Microscopy===
===Microscopic===
Classic Histo.<ref>{{Ref PBoD|1016-7}}</ref><ref name=Ref_GUP293>{{Ref GUP|293}}</ref>, 3 P's [[mnemonic]]:
Features - classic type:<ref>{{Ref PBoD|1016-7}}</ref><ref name=Ref_GUP293>{{Ref GUP|293}}</ref>, 3 P's [[mnemonic]]:
*Pale cytoplasm, with wisps of eosinophilic material; the cells are not completely clear, they have "cobwebs".
*Pale cytoplasm, with wisps of eosinophilic material; the cells are not completely clear, they have "cobwebs".
*Perinuclear clearing, i.e. a pale halo surrounds the nucleus - '''key feature'''.  
*Perinuclear clearing, i.e. a pale halo surrounds the nucleus - '''key feature'''.  
*Periphery of cell distinct, i.e. cell membrane is easy to discern.
*Periphery of cell distinct, i.e. cell membrane is easy to discern.


Eosinophilic variant:<ref name=Ref_GUP293>{{Ref GUP|293}}</ref>
Features - eosinophilic variant:<ref name=Ref_GUP293>{{Ref GUP|293}}</ref>
*Eosinophilic (finely granular) cytoplasm.
*Eosinophilic (finely granular) cytoplasm.
*Perinuclear clearing - '''key feature'''.
*Perinuclear clearing - '''key feature'''.
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Notes:
Notes:
*May have psammoma bodies.
*May have [[psammoma bodies]].


Image: [http://commons.wikimedia.org/wiki/File:Oncocytic_chromophobe_rcc_high_mag.jpg Oncocytic chromophobe RCC (wikimedia.org)].
Image: [http://commons.wikimedia.org/wiki/File:Oncocytic_chromophobe_rcc_high_mag.jpg Oncocytic chromophobe RCC (WC)].


===IHC===
===IHC===
48,833

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