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(→Granuloma annulare: split "granuloma annulare" into superficial and deep) |
(→Granuloma annulare: re-work section's micro descript.) |
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=Ref_WMSP478>{{Ref WMSP|478}}</ref> | Features:<ref name=Ref_WMSP478>{{Ref WMSP|478}}</ref> | ||
*Dermal palisading granuloma around: | *Dermal palisading [[granuloma]] around: | ||
** | **Necrotic collagen - '''key feature'''. | ||
***Nuclei "missing" - have undergone karyolysis. | |||
**Mucin. | |||
***Loose/pale, paucicellular, eosinophilic. | ***Loose/pale, paucicellular, eosinophilic. | ||
*Chronic inflammatory cells. | *Chronic inflammatory cells. | ||
Notes: | Notes: | ||
#There may be multiple small foci with intervening normal dermis.<ref name=Ref_Derm51>{{Ref Derm|51}}</ref> | |||
#Granuloma annulare can be subclassified into ''subcutaneous'' and ''interstitial''. | |||
#Histomorphologically similar to ''[[Rheumatoid nodule]]. | |||
DDx: | DDx: | ||
*Necrobiosis lipoidica - little mucin, no normal dermis between foci.<ref name=Ref_Derm51>{{Ref Derm|51}}</ref> | *Necrobiosis lipoidica - little mucin, no normal dermis between foci.<ref name=Ref_Derm51>{{Ref Derm|51}}</ref> | ||
*[[Rheumatoid nodule]]. | |||
Images: | Images: | ||
*[http://www.dermaamin.com/site/histopathology-of-the-skin/61-i/1813-interstitial-granuloma-annulare-.html Granuloma annulare (dermaamin.com)]. | *[http://www.dermaamin.com/site/histopathology-of-the-skin/61-i/1813-interstitial-granuloma-annulare-.html Granuloma annulare (dermaamin.com)]. | ||
==Keloid== | ==Keloid== |
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