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Difference between revisions of "Clear cell papillary renal cell tumour"
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Clear cell papillary renal cell tumour (view source)
Revision as of 22:14, 11 October 2022
, 22:14, 11 October 2022tweak
m (Michael moved page Clear cell papillary renal cell carcinoma to Clear cell papillary renal cell tumour: renamed in WHO) |
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| Image = Clear_cell_papillary_renal_cell_carcinoma_-_very_high_mag.jpg | | Image = Clear_cell_papillary_renal_cell_carcinoma_-_very_high_mag.jpg | ||
| Width = | | Width = | ||
| Caption = Clear cell papillary renal cell | | Caption = Clear cell papillary renal cell tumour. [[H&E stain]]. | ||
| Synonyms = clear cell tubulopapillary renal cell carcinoma | | Synonyms = previously known as ''clear cell tubulopapillary renal cell carcinoma'' and ''clear cell papillary renal cell carcinoma'' | ||
| Micro = low ([[ISUP nucleolar grade|ISUP nucleolar]]) grade apical nuclei, clear cells, pseudopapillae, cystic and/or tubular architectures | | Micro = low ([[ISUP nucleolar grade|ISUP nucleolar]]) grade apical nuclei, clear cells, pseudopapillae, cystic and/or tubular architectures | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[clear cell renal cell carcinoma]], [[papillary renal cell carcinoma]],[[Xp11.2 translocation carcinoma]] | | LMDDx = [[clear cell renal cell carcinoma]], [[papillary renal cell carcinoma]], [[Xp11.2 translocation carcinoma]] | ||
| Stains = | | Stains = | ||
| IHC = CK7 +ve, AMACR -ve, CD10 -ve, TFE3 -ve | | IHC = CK7 +ve, AMACR -ve, CD10 -ve, TFE3 -ve | ||
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| ClinDDx = other [[renal tumours]] | | ClinDDx = other [[renal tumours]] | ||
}} | }} | ||
'''Clear cell papillary renal cell | '''Clear cell papillary renal cell tumour''', abbreviated '''CCPRCT''', is a relatively common benign renal tumour. | ||
It is also known as '''clear cell tubulopapillary renal cell carcinoma''',<ref name=pmid21602815>{{Cite journal | last1 = Rohan | first1 = SM. | last2 = Xiao | first2 = Y. | last3 = Liang | first3 = Y. | last4 = Dudas | first4 = ME. | last5 = Al-Ahmadie | first5 = HA. | last6 = Fine | first6 = SW. | last7 = Gopalan | first7 = A. | last8 = Reuter | first8 = VE. | last9 = Rosenblum | first9 = MK. | title = Clear-cell papillary renal cell carcinoma: molecular and immunohistochemical analysis with emphasis on the von Hippel-Lindau gene and hypoxia-inducible factor pathway-related proteins. | journal = Mod Pathol | volume = 24 | issue = 9 | pages = 1207-20 | month = Sep | year = 2011 | doi = 10.1038/modpathol.2011.80 | PMID = 21602815 }}</ref> abbreviated '''CCTPRCC'''. | It was previously known as '''clear cell papillary renal cell carcinoma''', abbreviated '''CCPRCC''' | ||
It is also previously known as '''clear cell tubulopapillary renal cell carcinoma''',<ref name=pmid21602815>{{Cite journal | last1 = Rohan | first1 = SM. | last2 = Xiao | first2 = Y. | last3 = Liang | first3 = Y. | last4 = Dudas | first4 = ME. | last5 = Al-Ahmadie | first5 = HA. | last6 = Fine | first6 = SW. | last7 = Gopalan | first7 = A. | last8 = Reuter | first8 = VE. | last9 = Rosenblum | first9 = MK. | title = Clear-cell papillary renal cell carcinoma: molecular and immunohistochemical analysis with emphasis on the von Hippel-Lindau gene and hypoxia-inducible factor pathway-related proteins. | journal = Mod Pathol | volume = 24 | issue = 9 | pages = 1207-20 | month = Sep | year = 2011 | doi = 10.1038/modpathol.2011.80 | PMID = 21602815 }}</ref> abbreviated '''CCTPRCC'''. | |||
==General== | ==General== | ||
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<pre> | <pre> | ||
Left Kidney Mass, Core Biopsy: | Left Kidney Mass, Core Biopsy: | ||
- CLEAR CELL TUBULOPAPILARY RENAL CELL | - CLEAR CELL TUBULOPAPILARY RENAL CELL CELL TUMOUR, preliminary ISUP nucleolar | ||
grade 1 of 4, see comment. | grade 1 of 4, see comment. | ||
| Line 117: | Line 118: | ||
NEGATIVE: CD10. | NEGATIVE: CD10. | ||
The findings are in keeping with clear cell tubulopapillary renal cell | The findings are in keeping with clear cell tubulopapillary renal cell tumour. | ||
These tumours have a highly favourable clinical behaviour.[1,2] | These tumours have a highly favourable clinical behaviour.[1,2] | ||
1. Am J Surg Pathol. 2015 Dec;39(12):1621-34. DOI: 10.1097/PAS.0000000000000513 | 1. Am J Surg Pathol. 2015 Dec;39(12):1621-34. DOI: 10.1097/PAS.0000000000000513 | ||