Difference between revisions of "Medical liver disease"

[[File:1 Necrosis 2 680x512px.tif| Submassive hepatic necrosis.]]

[[File:2 Necrosis 2 680x512px.tif| Submassive hepatic necrosis.]]

[[File:3 Necrosis 2 680x512px.tif| Submassive hepatic necrosis.]]

[[File:4 Necrosis 2 680x512px.tif| Submassive hepatic necrosis.]]

[[File:5 Necrosis 2 680x512px.tif| Submassive hepatic necrosis.]]

[[File:6 Necrosis 2 680x512px.tif| Submassive hepatic necrosis.]]

Submassive hepatic necrosis. Patient had transaminases in the thousands that rapidly dropped to normal. Pink preserved parenchyma strews empty necrotic spaces (Row 1 Left 20X). Focus of necrosis with no apparent hepatocytes macrophages abuts apparently normal liver (Row 1 Right 200X). Iron stain shows the macrophages bear hemosiderin (Row 2 Left 200X). Reticulin stain highlights the recently dead liver cells (Row 2 Right 200X). Reticulin stain shows a necrotic bridge forming; the multiple small black circles preclude diagnosis of a fibrous bridge (Row 3 Left 200X).   Trichrome shows the necrotic bridge (“collapse”) lacks much collagen deposition, as would be expected for bridging fibrosis (Row 3 Right 200X).