Difference between revisions of "Hepatocellular carcinoma"

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2,468 bytes added ,  21:30, 5 September 2016
→‎Images: added a well-differentiated hepatoma with a tricky steatosis part
(→‎Images: added steatohepatitic variant)
(→‎Images: added a well-differentiated hepatoma with a tricky steatosis part)
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Image:Hepatocellular_carcinoma_intermed_mag.jpg | HCC - intermed mag. (WC)
Image:Hepatocellular_carcinoma_intermed_mag.jpg | HCC - intermed mag. (WC)
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[[File:1 HCC 3 680x512px.tif| Hepatocellular carcinoma with fragments of liver afflicted by steatosis & with regenerative, benign fragments.]]
[[File:2 HCC 3 680x512px.tif| Hepatocellular carcinoma with fragments of liver afflicted by steatosis & with regenerative, benign fragments.]]
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[[File:3 HCC 3 680x512px.tif| Hepatocellular carcinoma with fragments of liver afflicted by steatosis & with regenerative, benign fragments.]]
[[File:4 HCC 3 680x512px.tif| Hepatocellular carcinoma with fragments of liver afflicted by steatosis & with regenerative, benign fragments.]]
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[[File:5 HCC 3 680x512px.tif| Hepatocellular carcinoma with fragments of liver afflicted by steatosis & with regenerative, benign fragments.]]
[[File:6 HCC 3 680x512px.tif| Hepatocellular carcinoma with fragments of liver afflicted by steatosis & with regenerative, benign fragments.]]
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[[File:7 HCC 3 680x512px.tif| Hepatocellular carcinoma with fragments of liver afflicted by steatosis & with regenerative, benign fragments.]]
[[File:8 HCC 3 680x512px.tif| Hepatocellular carcinoma with fragments of liver afflicted by steatosis & with regenerative, benign fragments.]]
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Hepatocellular carcinoma with fragments of liver afflicted by steatosis & with regenerative, benign fragments. 
Fragments of liver with crowded nuclei, consistent with hepatoma, as well as with steatosis [arrows] (Row 1 Left 40X). Fragments of liver with crowded nuclei, consistent with hepatoma, as well as with larger amount of cytoplasm, consistent with regeneration [arrow](Row 1 Right 100X). The fatty liver below has aberrant-appearing nuclei, but not particularly crowded, in contrast to the fragment on top, which has crowded nuclei (Row 2 Left 200X). Reticulin stain shows apparent expansion of nuclei between black lines on the fatty liver, but this may also be seen with simple steatosis; on the crowded liver note the lack of definite expansion (Row 2 Right 200X).  The regenerative focus shows abundant cytoplasm (Row 3 Left 200X).  Reticulin on this regenerative focus shows preservation of the low number of nuclei between black lines  (Row 3 Right 200X). This typical hepatocellular focus shows crowding, occasional acini, and basophilia, similar to the focus seen in row 2. Note that some cells show apparent steatosis (Row 4 Left 200X).  Reticulin on this hepatocellular focus shows loss of reticulin fibers, with more than six nuclei between several black lines (Row 4 Right 200X).
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[[File:1 hcc 1 680x512px.tif|Fibrous bands dissect hepatocyte nodules, mostly hepatoma(Row 1 Left 20X).]]
[[File:1 hcc 1 680x512px.tif|Fibrous bands dissect hepatocyte nodules, mostly hepatoma(Row 1 Left 20X).]]
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