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| ==Columnar cell change== | | ==Columnar cell change== |
| *Abbreviated ''[[CCC]]''.
| | {{Main|Columnar cell change of the breast}} |
| *[[AKA]] ''blunt duct adenosis''.
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| ===General===
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| *Columnar cell change is associated with (benign) calcification - '''key point'''.
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| ===Microscopic===
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| Features:
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| *Secretory cells (line gland lumen) have columnar morphology.
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| *May have "apical snouts".
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| **Blebs or round balls eosinophilic material appear to be adjacent to the cell at their luminal surface.
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| **The snouts are attached to the cell-- appear as round ball only in the plane of section.
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| *Cytoplasm +/-eosinophilia.
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| *Often purple luminal calcifications
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| DDx:
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| *Flat epithelial atypia (>2 cell layers).{{Fact}}
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| **If the columnar cells shows low to intermediate grade atypia the process is termed "flat epithelial atypia"
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| **If higher grade atyia is present the lesion is termed "flat DCIS" (clinging carcinoma)
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| Image:
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| *[http://webpathology.com/image.asp?case=652&n=1 Columnar cell change (webpathology.com)].
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| ==Gynecomastoid hyperplasia== | | ==Gynecomastoid hyperplasia== |