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===Grading steatohepatitis=== | ===Grading steatohepatitis=== | ||
Grading inflammation:<ref name=pmid10484010> | Grading inflammation:<ref name=pmid10484010>{{Cite journal | last1 = Brunt | first1 = EM. | last2 = Janney | first2 = CG. | last3 = Di Bisceglie | first3 = AM. | last4 = Neuschwander-Tetri | first4 = BA. | last5 = Bacon | first5 = BR. | title = Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. | journal = Am J Gastroenterol | volume = 94 | issue = 9 | pages = 2467-74 | month = Sep | year = 1999 | doi = 10.1111/j.1572-0241.1999.01377.x | PMID = 10484010 }}ref> | ||
*Grade 1 - steatosis, occasional ballooning degeneration, PMNs. | *Grade 1 - steatosis, occasional ballooning degeneration, PMNs. | ||
*Grade 2 - obvious ballooning, obvious PMNs, chronic inflammation. | *Grade 2 - obvious ballooning, obvious PMNs, chronic inflammation. | ||
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Necroinflammatory grades Brunt 3, NAH 8. Fibrosis stage 4. Steatosis is pan-acinar (UL). Acinar inflammatory aggregates More than 4 inflammatory aggregates are seen in a 20X field (UR black arrowheads). Many cells show ballooning degeneration, with tufts/flocks of material cytoplasm (LL yellow arrowheads) Trichrome limns regenerative nodules (LR magenta arrowheads). Original oculars UL 4X, UR 20X, LL 40X (higher pixel photograph), LR 10X | Necroinflammatory grades Brunt 3, NAH 8. Fibrosis stage 4. Steatosis is pan-acinar (UL). Acinar inflammatory aggregates More than 4 inflammatory aggregates are seen in a 20X field (UR black arrowheads). Many cells show ballooning degeneration, with tufts/flocks of material cytoplasm (LL yellow arrowheads) Trichrome limns regenerative nodules (LR magenta arrowheads). Original oculars UL 4X, UR 20X, LL 40X (higher pixel photograph), LR 10X | ||
===Image=== | ===Image=== |
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