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(→Tubular adenoma (colon) - negative of high-grade dysplasia: new section) |
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The histomorphologic features in this specimen are those of a benign, chronic process; however, they are not distinctive. They are compatible with (1) a juvenile polyp, (2) a polypoid solitary rectal ulcer, and (3) an inflammatory pseudopolyp. As an inflammatory pseudopolyp is in the pathologic differential diagnosis, inflammatory bowel disease should be considered clinically. | The histomorphologic features in this specimen are those of a benign, chronic process; however, they are not distinctive. They are compatible with (1) a juvenile polyp, (2) a polypoid solitary rectal ulcer, and (3) an inflammatory pseudopolyp. As an inflammatory pseudopolyp is in the pathologic differential diagnosis, inflammatory bowel disease should be considered clinically. | ||
== Tubular adenoma | == Tubular adenoma - low-grade dysplasia == | ||
===Microscopic description=== | ===Microscopic description=== | ||
The sections show normal colonic-type mucosa and abnormal mucosal glands that have, from crypt base to luminal aspect, nuclear pseudostratification/crowding, nuclear hyperchromasia and enlargement, goblet cell paucity, and cytoplasmic hyperchromasia. | The sections show normal colonic-type mucosa and abnormal mucosal glands that have, from crypt base to luminal aspect, nuclear pseudostratification/crowding, nuclear hyperchromasia and enlargement, goblet cell paucity, and cytoplasmic hyperchromasia. |
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