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*Desmin +ve. | *Desmin +ve. | ||
*ER and PR +ve (6 of 9 cases:<ref name=pmid25517956/>). | *ER and PR +ve (6 of 9 cases:<ref name=pmid25517956/>). | ||
==Sign out== | |||
<pre> | |||
Mass Lesion, Right Kidney, Core Biopsy: | |||
- Benign leiomyoma with hyalinization and without atypia, see comment. | |||
- Renal parenchyma within normal limits present. | |||
- NEGATIVE for malignancy. | |||
Comment: | |||
The tumour stains as follows: | |||
POSITIVE: desmin, SMA, ER, PR. | |||
NEGATIVE: HMB-45. | |||
Proliferation (Ki-67): 0%. | |||
The tumour histology and immunoprofile is that of a leiomyoma. Renal leiomyomas are very rare lesions; a large contemporary series has only 9 cases. [1] | |||
Correlation with radiology is suggested. | |||
1. Am J Surg Pathol. 2015 Mar;39(3):349-56. | |||
</pre> | |||
===Micro=== | |||
The sections show tumour with a fascicular architecture and hyalinization. No adipose tissue is seen. Necrosis is not identified. Nuclear atypia is not seen. Mitotic activity is not readily apparent. Benign unremarkable renal parenchyma is present. | |||
==See also== | ==See also== |
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