Difference between revisions of "Papillary thyroid carcinoma"

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=====Microscopic=====
=====Microscopic=====
Features:
Features:
*Cribriform architectural pattern.
*Circumscribed or even encapsulated neoplasm.
*Morules - balls of tissue.
*Morules - interspersed balls of squamoid cells
**no keritinization or intercellular bridges.
**Homogenous, lightly eosinophilic glassy nuclei
.
*Follicles
**Cribriform, papillary, trabecular and solid patterns.
**Columnar or cuboidal cells.
**Little colloid
**Papillary carcinoma nuclear features.
 
DDX:
*Papillary thyroid carcinoma
*Papillary thyroid carcinoma, tall cell variant
 
<gallery>
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant MP3 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - Medium power (SKB)
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant HP2 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - High power (SKB)
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant HP3 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - high power]]
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant CDX2 HP 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - CDX2 (SKB)
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant P16 HP 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - p16 (SKB)
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant P16 HP3 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - p16 (SKB)
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant ER HP 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - ER (SKB)
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant betaCatenin HP 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - beta catenin (SKB)
</gallery>


====Papillary thyroid carcinoma diffuse sclerosing variant====
====Papillary thyroid carcinoma diffuse sclerosing variant====
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