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Difference between revisions of "Extramammary Paget disease"
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→DDx
(→DDx) |
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===DDx=== | ===DDx=== | ||
*[[Malignant melanoma in situ]] - atypical cells are mostly basilar with upward migration. | *[[Malignant melanoma in situ]] - atypical cells are mostly basilar with upward migration. | ||
*Squamous cell carcinoma in situ "[[Bowen disease]]" | *Squamous cell carcinoma in situ "[[Bowen disease]]" | ||
**Pagetoid squamous cell carcinoma in situ can look identical to extramammary Paget disease | |||
**But should have some areas of typical SCCIS with full thickness cohesive atypia | |||
*Pagetoid vulvar/anal/penil HPV associated intraepithelial neoplasia - Pagetoid areas often merge into areas of typical VIN | *Pagetoid vulvar/anal/penil HPV associated intraepithelial neoplasia - Pagetoid areas often merge into areas of typical VIN | ||
*'Paget disease' associated with an underlying local carcinoma - apocrine, Bartholin's duct etc (rare). | |||
*Notice that mammary Paget disease and Toker cell hyperplasia are not part of this DDX (wrong location) except possibly in the rare case of EMPD arising in the axilla where mammary Paget disease arising from a ectopic nipple or ectopic breast tissue may be a consideration. | *Notice that mammary Paget disease and Toker cell hyperplasia are not part of this DDX (wrong location) except possibly in the rare case of EMPD arising in the axilla where mammary Paget disease arising from a ectopic nipple or ectopic breast tissue may be a consideration. | ||