Difference between revisions of "Clear cell carcinoma of the uterine cervix"

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==Microscopic==
==Microscopic==
Features:<ref name=pmid22885379/>
Features:<ref name=pmid22885379/>
*Like [[clear cell carcinoma]] elsewhere:
*Clear cytoplasm - '''key feature'''.
**Clear cytoplasm - '''key feature'''.
**May be focal/absent!
***May be absent!
**Cells have large free/luminal surface area (hobnailing pattern) and small non-free surface.
**Cells have large free/luminal surface area (hobnailing pattern) and small non-free surface.
**Moderate-to-severe [[nuclear pleomorphism]].
*Moderate-to-severe [[nuclear pleomorphism]].
**Tubular and/or cystic morphology.
*Tubular and/or cystic morphology.
***May be (simple) papillary and/or solid.
**May be (simple) papillary and/or solid.
*Adenosis - typically adjacent.
*Adenosis - typically adjacent.


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*[[Clear cell carcinoma of the endometrium]] - diagnosis based on clinico-radiologic correlation (IHC & histology not useful).<ref name=pmid22885379>{{Cite journal  | last1 = Offman | first1 = SL. | last2 = Longacre | first2 = TA. | title = Clear cell carcinoma of the female genital tract (not everything is as clear as it seems). | journal = Adv Anat Pathol | volume = 19 | issue = 5 | pages = 296-312 | month = Sep | year = 2012 | doi = 10.1097/PAP.0b013e31826663b1 | PMID = 22885379 }}</ref>
*[[Clear cell carcinoma of the endometrium]] - diagnosis based on clinico-radiologic correlation (IHC & histology not useful).<ref name=pmid22885379>{{Cite journal  | last1 = Offman | first1 = SL. | last2 = Longacre | first2 = TA. | title = Clear cell carcinoma of the female genital tract (not everything is as clear as it seems). | journal = Adv Anat Pathol | volume = 19 | issue = 5 | pages = 296-312 | month = Sep | year = 2012 | doi = 10.1097/PAP.0b013e31826663b1 | PMID = 22885379 }}</ref>
*[[Serous carcinoma of the endometrium]].
*[[Serous carcinoma of the endometrium]].
*[[Serous carcinoma of the uterine cervix]].
*[[Serous carcinoma]] of the uterine cervix.
*[[Mesonephric adenocarcinoma]].
*[[Mesonephric adenocarcinoma]].


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