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Difference between revisions of "Pediatric pathology"
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→Hypoxic-ischemic encephalopathy
(→Hypoxic-ischemic encephalopathy: +seizure) |
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*HIE in perinatal period may be unique to the specific time of the injury, i.e. the type of hypoxic insults vary by developmental stage.<ref name=pmid11876572>{{cite journal |author=Grafe MR, Kinney HC |title=Neuropathology associated with stillbirth |journal=Semin. Perinatol. |volume=26 |issue=1 |pages=83–8 |year=2002 |month=February |pmid=11876572 |doi= |url=}}</ref> | *HIE in perinatal period may be unique to the specific time of the injury, i.e. the type of hypoxic insults vary by developmental stage.<ref name=pmid11876572>{{cite journal |author=Grafe MR, Kinney HC |title=Neuropathology associated with stillbirth |journal=Semin. Perinatol. |volume=26 |issue=1 |pages=83–8 |year=2002 |month=February |pmid=11876572 |doi= |url=}}</ref> | ||
**Some hypoxic injuries that are prenatal do not occur after birth. | **Some hypoxic injuries that are prenatal do not occur after birth. | ||
***''Pontosubicular necrosis'' is prenatal; the subiculum postnatal (like in adults) is resistant to hypoxic-ischemic insults. | |||
**Hypoxic-ischemic insults are predominantly in the white matter. | **Hypoxic-ischemic insults are predominantly in the white matter. | ||
*HIE is the most common cause of neonatal seizures and often difficult to control with anticonvulsants.<ref>URL: [http://emedicine.medscape.com/article/973501-overview http://emedicine.medscape.com/article/973501-overview]. Accessed on: 7 January 2011.</ref> | *HIE is the most common cause of neonatal seizures and often difficult to control with anticonvulsants.<ref>URL: [http://emedicine.medscape.com/article/973501-overview http://emedicine.medscape.com/article/973501-overview]. Accessed on: 7 January 2011.</ref> | ||