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[[Image:High grade squamous intraepithelial lesion - 2 - p16 -- high mag.jpg|thumb|right|200px|HSIL showing the characteristic p16 staining.]] | |||
'''p16''' is a commonly used [[immunostain]]. It can be considered a surrogate marker for [[HPV]] infection. | '''p16''' is a commonly used [[immunostain]]. It can be considered a surrogate marker for [[HPV]] infection. | ||
p16, like most other "p" stains, is a nuclear stain. | p16, like most other "p" stains, is a nuclear stain. | ||
==Pattern== | ==Pattern== | ||
*Nuclear stain. | *Nuclear stain +/- cytoplasmic staining. | ||
==Use== | ==Use== |
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