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'''Angiokeratoma''' is a benign [[skin]] lesion. | |||
==General== | |||
*Rare. | |||
*May be seen in the context of [[Fabry disease]].<ref name=pmid16403380/> | |||
Notes: | |||
*Shouldn't be confused with ''[[angiofibroma]]'' which is associated [[tuberous sclerosis]]. | |||
==Gross== | |||
*Dark lesions. | |||
Clinical DDx: | |||
*[[Melanocytic lesions]]. | |||
===Images=== | |||
<gallery> | |||
Image:Angiokeratoma_of_the_Scrotum_7.jpg | Angiokeratoma. (WC) | |||
</gallery> | |||
==Microscopic== | |||
Features:<ref name=pmid16403380>{{Cite journal | last1 = Karen | first1 = JK. | last2 = Hale | first2 = EK. | last3 = Ma | first3 = L. | title = Angiokeratoma corporis diffusum (Fabry disease). | journal = Dermatol Online J | volume = 11 | issue = 4 | pages = 8 | month = | year = 2005 | doi = | PMID = 16403380 }}</ref> | |||
#Ectatic superficial dermal vessels. | |||
#Overlying hyperkeratosis (thick stratum corneum). | |||
*Should have "epidermal collarette".<ref name=Ref_Derm548>{{Ref Derm|548}}</ref> | |||
**Vascular space surrounded by epidermis on three sides. | |||
Others features:{{fact}} | |||
*Irregular [[acanthosis]]. | |||
*Longer rete ridges. | |||
DDx: | |||
*[[Venous lake]]. | |||
===Images=== | |||
<gallery> | |||
Image:Angiokeratoma_-_low_mag.jpg | Angiokeratoma - low mag. (WC/Nephron) | |||
Image:Angiokeratoma_-_intermed_mag.jpg | Angiokeratoma - intermed. mag. (WC/Nephron) | |||
</gallery> | |||
www: | |||
*[http://www.pathologyoutlines.com/images/skintumorangiokerat1.jpg Angiokeratoma (pathologyoutlines.com)]. | |||
==Sign out== | |||
<pre> | |||
SKIN LESION, LEFT POPITEAL FOSSA, PUNCH BIOPSY: | |||
- ANGIOKERATOMA. | |||
</pre> | |||
==See also== | |||
*[[Non-malignant skin disease]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:#redirect [[Non-malignant_skin_disease]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] |
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