48,830
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| Micro = nuclear membrane irregularies, nuclear hyperchromasia, +/-clear perinuclear halos (koilocytic change), +/-nuclear enlargement, large [[NC ratio]] (usually ~ 1:3), +/-mitoses (lower third) | | Micro = nuclear membrane irregularies, nuclear hyperchromasia, +/-clear perinuclear halos (koilocytic change), +/-nuclear enlargement, large [[NC ratio]] (usually ~ 1:3), +/-mitoses (lower third) | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[high-grade squamous intraepithelial lesion]] | | LMDDx = [[high-grade squamous intraepithelial lesion]], [[squamous metaplasia of the uterine cervix|squamous metaplasia]], [[reactive squamous epithelium of the uterine cervix|reactive changes]], normal cervix | ||
| Stains = | | Stains = | ||
| IHC = p16 -ve (or lower 1/3 +ve), Ki-67 occasional cells - lower half | | IHC = p16 -ve (or lower 1/3 +ve), Ki-67 occasional cells - lower half | ||
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DDx: | DDx: | ||
*[[High-grade squamous intraepithelial lesion]]. | *[[High-grade squamous intraepithelial lesion]]. | ||
*[[ | *[[Squamous metaplasia of the uterine cervix]]. | ||
*[[Reactive squamous epithelium of the uterine cervix]]. | |||
*Normal cervix. | |||
===Koilocytes versus benign squamous=== | ===Koilocytes versus benign squamous=== |
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