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*[[High-grade squamous intraepithelial lesion]]. | *[[High-grade squamous intraepithelial lesion]]. | ||
*[[Uterine cervix with reactive changes]]. | *[[Uterine cervix with reactive changes]]. | ||
===Koilocytes versus benign squamous=== | |||
Koilocytes: | |||
*Perinuclear clearing. | |||
*Nuclear changes. | |||
**Size similar (or larger) to those in the basal layer of the epithelium. | |||
**Nuclear enlargement should be evident on low power, i.e. 25x. <ref>V. Dube 2008.</ref> | |||
**Central location - nucleus should be smack in the middle of the cell. | |||
Notes: | |||
# Both perinuclear clearing and nuclear changes are essential. | |||
# Benign cells have a small nucleus that is peripheral. | |||
===Images=== | |||
<gallery> | |||
Image: Low-grade squamous intraepithelial lesion -- intermed mag.jpg | LSIL - intermed. mag. (WC) | |||
Image: Low-grade squamous intraepithelial lesion -- p16 - intermed mag.jpg | LSIL - intermed. mag. (WC) | |||
Image: Low-grade squamous intraepithelial lesion -- high mag.jpg | LSIL - high mag. (WC) | |||
Image: Low-grade squamous intraepithelial lesion -- very high mag.jpg | LSIL - very high mag. (WC) | |||
</gallery> | |||
<gallery> | |||
Image:Cervical intraepithelial neoplasia (2) koilocytosis.jpg| CIN I. (WC/KGH) | |||
</gallery> | |||
www: | |||
*[http://www.flickr.com/photos/jian-hua_qiao_md/3987000055/ CIN 1 (flickr.com/Qiao)]. | |||
*[http://www.eurocytology.eu/static/eurocytology/eng/cervical/mod6img1a.html CIN 1 (eurocytology.eu)]. | |||
==See also== | ==See also== |
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