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Difference between revisions of "Sertoli cell tumour"
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| Micro = groups of cells in ''cords'' or ''trabeculae'', cells have light staining bubbly cytoplasm +/- large cytoplasmic vacuoles, slightly irregular nucleoli, granular irregular appearing chromatin | | Micro = groups of cells in ''cords'' or ''trabeculae'', cells have light staining bubbly cytoplasm +/- large cytoplasmic vacuoles, slightly irregular nucleoli, granular irregular appearing chromatin | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[granulosa cell tumour]], epithelioid [[adenomatoid tumour]], [[sertoli cell nodule]] | | LMDDx = [[granulosa cell tumour]], epithelioid [[adenomatoid tumour]], [[sertoli cell nodule]], [[Sertoli-Leydig tumour]] | ||
| Stains = | | Stains = | ||
| IHC = alpha-inhibin, calretinin | | IHC = alpha-inhibin, calretinin | ||
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==General== | ==General== | ||
*Arises from ''Sertoli cells'' ([[AKA]] nurse cells). | *Arises from ''Sertoli cells'' ([[AKA]] nurse cells). | ||
*Occasionally seen in women.<ref name=pmid20349797>{{Cite journal | last1 = Zizi-Sermpetzoglou | first1 = A. | last2 = Petrakopoulou | first2 = N. | last3 = Tepelenis | first3 = N. | last4 = Savvaidou | first4 = V. | last5 = Manoloudaki | first5 = K. | last6 = Katsoulis | first6 = M. | title = Pure Sertoli cell tumor. a case report and review of the literature. | journal = Eur J Gynaecol Oncol | volume = 31 | issue = 1 | pages = 117-9 | month = | year = 2010 | doi = | PMID = 20349797 }}</ref> | |||
May be seen in several syndrome - esp. if there is calcification: | May be seen in several syndrome - esp. if there is calcification: | ||