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*May be very subtle, i.e. difficult to differentiate from normal glands. | *May be very subtle, i.e. difficult to differentiate from normal glands. | ||
**"Deep glands" that look bland shouldn't immediately be dismissed as benign. | **"Deep glands" that look bland shouldn't immediately be dismissed as benign. | ||
Subtypes: | |||
*[[Mucinous carcinoma]].<ref name=pmid23106580/> | |||
DDx: | DDx: | ||
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Image:Gallbladder adenocarcinoma (3) lymphatic invasion histopathology.jpg | GB carcinoma - LVI. (WC) | Image:Gallbladder adenocarcinoma (3) lymphatic invasion histopathology.jpg | GB carcinoma - LVI. (WC) | ||
</gallery> | </gallery> | ||
==IHC== | |||
Features - conventional:<ref name=pmid23106580>{{Cite journal | last1 = Dursun | first1 = N. | last2 = Escalona | first2 = OT. | last3 = Roa | first3 = JC. | last4 = Basturk | first4 = O. | last5 = Bagci | first5 = P. | last6 = Cakir | first6 = A. | last7 = Cheng | first7 = J. | last8 = Sarmiento | first8 = J. | last9 = Losada | first9 = H. | title = Mucinous carcinomas of the gallbladder: clinicopathologic analysis of 15 cases identified in 606 carcinomas. | journal = Arch Pathol Lab Med | volume = 136 | issue = 11 | pages = 1347-58 | month = Nov | year = 2012 | doi = 10.5858/arpa.2011-0447-OA | PMID = 23106580 }}</ref> | |||
*CK7 +ve (7 of 8 cases. | |||
*CK20 -ve (7 of 8 cases). | |||
*CDX2 -ve (8 of 8 cases). | |||
==See also== | ==See also== |
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